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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCL2
All Species:
17.88
Human Site:
T225
Identified Species:
32.78
UniProt:
Q8N4E4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4E4
NP_689614.2
241
28071
T225
M
V
S
S
I
R
N
T
S
I
H
D
D
S
D
Chimpanzee
Pan troglodytes
XP_526622
241
28036
T225
M
V
S
S
I
R
N
T
S
I
H
D
D
S
D
Rhesus Macaque
Macaca mulatta
XP_001087954
241
27921
T225
M
V
S
S
I
R
N
T
S
I
H
D
D
S
D
Dog
Lupus familis
XP_532378
335
37869
T318
M
V
S
S
I
R
N
T
S
I
Y
D
D
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q78Y63
240
27751
I225
M
V
S
S
I
R
N
I
S
I
Y
D
S
D
S
Rat
Rattus norvegicus
Q4KLJ8
240
27681
V220
P
K
K
A
I
K
D
V
L
L
S
S
V
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520868
256
30002
T232
V
S
S
S
I
R
N
T
S
I
Y
D
D
S
N
Chicken
Gallus gallus
XP_420702
244
28537
I225
M
T
L
S
M
Q
N
I
S
V
H
E
N
M
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P268
239
27638
C224
Q
L
M
T
S
I
R
C
S
A
N
T
H
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MR62
240
27421
P222
E
I
T
E
D
P
R
P
Q
I
R
D
K
M
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794769
241
27321
I224
Q
V
R
S
T
L
N
I
F
S
G
R
N
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64628
211
24432
I179
R
I
A
R
A
Q
V
I
H
Y
D
G
E
S
S
Baker's Yeast
Sacchar. cerevisiae
Q12017
286
32775
V267
G
I
R
G
K
F
N
V
G
I
G
G
N
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
97
65.9
N.A.
87.1
56
N.A.
76.5
72.5
N.A.
55.5
N.A.
40.2
N.A.
N.A.
44.8
Protein Similarity:
100
99.5
99.5
70.4
N.A.
95.8
75.5
N.A.
89.4
87.3
N.A.
74.2
N.A.
66.3
N.A.
N.A.
69.7
P-Site Identity:
100
100
100
80
N.A.
66.6
13.3
N.A.
73.3
40
N.A.
13.3
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
73.3
40
N.A.
93.3
73.3
N.A.
33.3
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
29.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
8
54
39
16
54
% D
% Glu:
8
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
0
8
0
16
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
31
0
8
0
0
% H
% Ile:
0
24
0
0
54
8
0
31
0
62
0
0
0
0
0
% I
% Lys:
0
8
8
0
8
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
8
8
0
0
8
0
0
8
8
0
0
0
0
8
% L
% Met:
47
0
8
0
8
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
0
0
0
0
0
70
0
0
0
8
0
24
0
24
% N
% Pro:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
0
0
16
0
0
8
0
0
0
0
8
0
% Q
% Arg:
8
0
16
8
0
47
16
0
0
0
8
8
0
16
0
% R
% Ser:
0
8
47
62
8
0
0
0
62
8
8
8
8
39
16
% S
% Thr:
0
8
8
8
8
0
0
39
0
0
0
8
0
8
0
% T
% Val:
8
47
0
0
0
0
8
16
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
24
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _