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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A24
All Species:
9.09
Human Site:
S81
Identified Species:
25
UniProt:
Q8N4F4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4F4
NP_001129978
322
35933
S81
R
I
S
I
P
L
D
S
N
L
R
P
Q
K
C
Chimpanzee
Pan troglodytes
XP_522042
534
59836
S81
R
I
S
I
P
L
D
S
N
M
R
P
E
K
C
Rhesus Macaque
Macaca mulatta
XP_001084749
442
48289
E81
I
P
P
G
P
N
W
E
P
H
Q
C
R
R
F
Dog
Lupus familis
XP_533255
552
61678
S81
R
I
S
I
P
L
D
S
N
L
R
P
E
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFZ5
553
60176
P81
A
V
S
I
P
P
G
P
D
Q
Q
P
H
Q
C
Rat
Rattus norvegicus
Q3ZAV1
553
60226
P81
A
V
S
I
P
P
G
P
D
Q
R
P
H
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507099
556
61556
Q81
R
V
S
I
P
L
D
Q
N
Q
K
L
E
K
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J54
558
62434
R81
D
A
D
G
Q
P
D
R
C
L
E
Y
V
E
V
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
L74
R
A
T
V
P
L
G
L
N
G
K
L
E
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.7
38
39.3
N.A.
29.1
28.9
N.A.
30
N.A.
24
24.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47
48.1
48.9
N.A.
40.1
39.9
N.A.
41.7
N.A.
39
37.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
6.6
93.3
N.A.
33.3
40
N.A.
60
N.A.
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
60
60
N.A.
80
N.A.
20
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
78
% C
% Asp:
12
0
12
0
0
0
56
0
23
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
12
0
45
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
23
0
0
34
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
23
0
0
% H
% Ile:
12
34
0
67
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
23
0
0
45
0
% K
% Leu:
0
0
0
0
0
56
0
12
0
34
0
23
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
56
0
0
0
0
0
0
% N
% Pro:
0
12
12
0
89
34
0
23
12
0
0
56
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
12
0
34
23
0
12
23
0
% Q
% Arg:
56
0
0
0
0
0
0
12
0
0
45
0
12
23
0
% R
% Ser:
0
0
67
0
0
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
34
0
12
0
0
0
0
0
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _