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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF175
All Species:
12.42
Human Site:
S221
Identified Species:
24.85
UniProt:
Q8N4F7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4F7
NP_775933.1
328
38267
S221
V
S
R
L
P
T
R
S
L
S
D
N
I
C
A
Chimpanzee
Pan troglodytes
XP_001155746
328
38119
S221
V
S
G
L
P
T
R
S
L
S
D
N
I
C
A
Rhesus Macaque
Macaca mulatta
XP_001088194
328
38179
S221
V
S
G
L
P
T
R
S
L
S
D
N
I
C
A
Dog
Lupus familis
XP_855302
318
37276
S211
M
S
G
M
P
T
R
S
L
G
D
N
V
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1Z9
327
37968
H220
E
S
G
M
P
T
K
H
L
S
D
S
V
C
A
Rat
Rattus norvegicus
NP_001101010
327
37954
H220
E
S
G
M
P
T
K
H
L
S
D
S
V
C
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417284
325
37745
H218
A
S
G
M
P
T
K
H
L
S
D
S
V
C
A
Frog
Xenopus laevis
Q6DD32
327
37920
H220
A
S
G
M
P
T
K
H
L
S
D
S
V
C
A
Zebra Danio
Brachydanio rerio
NP_956602
293
34428
V203
G
Q
K
I
F
V
D
V
D
E
E
G
I
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573247
321
37626
H214
P
Q
G
I
P
T
R
H
L
D
Q
N
V
C
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09251
409
47609
H290
P
E
G
L
P
K
K
H
L
E
D
G
V
C
A
Sea Urchin
Strong. purpuratus
XP_001176116
331
38964
A224
K
T
G
L
P
G
R
A
L
E
P
Y
I
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
87.1
N.A.
68.2
67.9
N.A.
N.A.
68.5
67
71.6
N.A.
54.2
N.A.
38.8
57.7
Protein Similarity:
100
99
98.1
89.9
N.A.
82.9
82.9
N.A.
N.A.
82.6
83.5
82.6
N.A.
69.8
N.A.
57.7
73.1
P-Site Identity:
100
93.3
93.3
66.6
N.A.
53.3
53.3
N.A.
N.A.
53.3
53.3
6.6
N.A.
46.6
N.A.
40
46.6
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
80
80
N.A.
N.A.
80
80
26.6
N.A.
60
N.A.
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
9
0
0
0
0
0
0
92
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
92
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
9
75
0
0
0
0
% D
% Glu:
17
9
0
0
0
0
0
0
0
25
9
0
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
84
0
0
9
0
0
0
9
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
0
0
0
0
0
42
9
0
% I
% Lys:
9
0
9
0
0
9
42
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
42
0
0
0
0
92
0
0
0
0
0
0
% L
% Met:
9
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% N
% Pro:
17
0
0
0
92
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
17
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
50
0
0
0
0
0
0
0
0
% R
% Ser:
0
67
0
0
0
0
0
34
0
59
0
34
0
0
0
% S
% Thr:
0
9
0
0
0
75
0
0
0
0
0
0
0
0
0
% T
% Val:
25
0
0
0
0
9
0
9
0
0
0
0
59
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _