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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF175 All Species: 33.64
Human Site: T124 Identified Species: 67.27
UniProt: Q8N4F7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4F7 NP_775933.1 328 38267 T124 S Y I L F R A T R K P L S G R
Chimpanzee Pan troglodytes XP_001155746 328 38119 T124 S Y I L F R A T R K P L S G R
Rhesus Macaque Macaca mulatta XP_001088194 328 38179 T124 S Y I L F R A T R K P L S G R
Dog Lupus familis XP_855302 318 37276 T114 S Y I L F R A T R K P L S G R
Cat Felis silvestris
Mouse Mus musculus Q8R1Z9 327 37968 T123 A F V T F R A T R K P L V Q T
Rat Rattus norvegicus NP_001101010 327 37954 T123 A F V T F R A T R K P L V Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417284 325 37745 T121 A F V T F K A T R K P L V Q T
Frog Xenopus laevis Q6DD32 327 37920 T123 A Y I T Y K A T R K P L L Q T
Zebra Danio Brachydanio rerio NP_956602 293 34428 L106 R M V Y K W F L L I Y K L S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573247 321 37626 I117 A L V M R R A I S K P I Q G T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09251 409 47609 S193 A F I W L K A S A Q H I S G G
Sea Urchin Strong. purpuratus XP_001176116 331 38964 T127 S I I V Y K A T R K P L P G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.9 87.1 N.A. 68.2 67.9 N.A. N.A. 68.5 67 71.6 N.A. 54.2 N.A. 38.8 57.7
Protein Similarity: 100 99 98.1 89.9 N.A. 82.9 82.9 N.A. N.A. 82.6 83.5 82.6 N.A. 69.8 N.A. 57.7 73.1
P-Site Identity: 100 100 100 100 N.A. 53.3 53.3 N.A. N.A. 46.6 53.3 0 N.A. 33.3 N.A. 26.6 60
P-Site Similarity: 100 100 100 100 N.A. 73.3 73.3 N.A. N.A. 73.3 73.3 6.6 N.A. 60 N.A. 66.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 0 0 92 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 34 0 0 59 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 59 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 9 59 0 0 0 0 9 0 9 0 17 0 0 0 % I
% Lys: 0 0 0 0 9 34 0 0 0 84 0 9 0 0 0 % K
% Leu: 0 9 0 34 9 0 0 9 9 0 0 75 17 0 0 % L
% Met: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 84 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 9 34 0 % Q
% Arg: 9 0 0 0 9 59 0 0 75 0 0 0 0 0 34 % R
% Ser: 42 0 0 0 0 0 0 9 9 0 0 0 42 9 0 % S
% Thr: 0 0 0 34 0 0 0 75 0 0 0 0 0 0 50 % T
% Val: 0 0 42 9 0 0 0 0 0 0 0 0 25 0 0 % V
% Trp: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 42 0 9 17 0 0 0 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _