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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF175
All Species:
29.7
Human Site:
T219
Identified Species:
59.39
UniProt:
Q8N4F7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4F7
NP_775933.1
328
38267
T219
Y
S
V
S
R
L
P
T
R
S
L
S
D
N
I
Chimpanzee
Pan troglodytes
XP_001155746
328
38119
T219
Y
S
V
S
G
L
P
T
R
S
L
S
D
N
I
Rhesus Macaque
Macaca mulatta
XP_001088194
328
38179
T219
Y
S
V
S
G
L
P
T
R
S
L
S
D
N
I
Dog
Lupus familis
XP_855302
318
37276
T209
Y
S
M
S
G
M
P
T
R
S
L
G
D
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1Z9
327
37968
T218
Y
S
E
S
G
M
P
T
K
H
L
S
D
S
V
Rat
Rattus norvegicus
NP_001101010
327
37954
T218
Y
S
E
S
G
M
P
T
K
H
L
S
D
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417284
325
37745
T216
Y
S
A
S
G
M
P
T
K
H
L
S
D
S
V
Frog
Xenopus laevis
Q6DD32
327
37920
T218
Y
S
A
S
G
M
P
T
K
H
L
S
D
S
V
Zebra Danio
Brachydanio rerio
NP_956602
293
34428
V201
V
C
G
Q
K
I
F
V
D
V
D
E
E
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573247
321
37626
T212
Y
T
P
Q
G
I
P
T
R
H
L
D
Q
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09251
409
47609
K288
Y
T
P
E
G
L
P
K
K
H
L
E
D
G
V
Sea Urchin
Strong. purpuratus
XP_001176116
331
38964
G222
Y
T
K
T
G
L
P
G
R
A
L
E
P
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
87.1
N.A.
68.2
67.9
N.A.
N.A.
68.5
67
71.6
N.A.
54.2
N.A.
38.8
57.7
Protein Similarity:
100
99
98.1
89.9
N.A.
82.9
82.9
N.A.
N.A.
82.6
83.5
82.6
N.A.
69.8
N.A.
57.7
73.1
P-Site Identity:
100
93.3
93.3
66.6
N.A.
53.3
53.3
N.A.
N.A.
53.3
53.3
6.6
N.A.
40
N.A.
33.3
40
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
80
80
N.A.
N.A.
80
80
26.6
N.A.
60
N.A.
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
9
9
75
0
0
% D
% Glu:
0
0
17
9
0
0
0
0
0
0
0
25
9
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
84
0
0
9
0
0
0
9
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
42
% I
% Lys:
0
0
9
0
9
0
0
9
42
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
42
0
0
0
0
92
0
0
0
0
% L
% Met:
0
0
9
0
0
42
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% N
% Pro:
0
0
17
0
0
0
92
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
50
0
0
0
0
0
0
% R
% Ser:
0
67
0
67
0
0
0
0
0
34
0
59
0
34
0
% S
% Thr:
0
25
0
9
0
0
0
75
0
0
0
0
0
0
0
% T
% Val:
9
0
25
0
0
0
0
9
0
9
0
0
0
0
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
92
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _