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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf68 All Species: 13.64
Human Site: S284 Identified Species: 37.5
UniProt: Q8N4H0 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4H0 NP_001034484.2 392 45058 S284 R I V L R S D S S S C L D S S
Chimpanzee Pan troglodytes XP_001138482 386 44359 S278 R I V L R S D S S S C L D S S
Rhesus Macaque Macaca mulatta XP_001085450 392 45205 S284 R I I L R S D S S S R L D S S
Dog Lupus familis XP_851964 407 46522 S298 I L R K D S P S S L D S S K F
Cat Felis silvestris
Mouse Mus musculus Q3U6K5 488 56083 F317 G R D F E D P F E R C E E Y L
Rat Rattus norvegicus Q6AYJ3 398 46089 S293 R I V L R S Q S P P P L N S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505251 166 19266 E61 A D I L E L L E C Y T T K F E
Chicken Gallus gallus NP_001026453 204 23148 T99 P V G E I L A T Y E E N T R D
Frog Xenopus laevis NP_001089751 396 44772 K290 H A S R L S E K D F L D S G G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 94.3 70.2 N.A. 27.4 60.7 N.A. 22.1 26 38.6 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.4 96.4 79.1 N.A. 41.1 71.1 N.A. 31.1 37.5 56.8 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 20 N.A. 6.6 60 N.A. 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 26.6 N.A. 13.3 66.6 N.A. 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 34 0 0 0 0 % C
% Asp: 0 12 12 0 12 12 34 0 12 0 12 12 34 0 12 % D
% Glu: 0 0 0 12 23 0 12 12 12 12 12 12 12 0 12 % E
% Phe: 0 0 0 12 0 0 0 12 0 12 0 0 0 12 12 % F
% Gly: 12 0 12 0 0 0 0 0 0 0 0 0 0 12 23 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 45 23 0 12 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 0 0 12 0 0 0 0 12 12 0 % K
% Leu: 0 12 0 56 12 23 12 0 0 12 12 45 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % N
% Pro: 12 0 0 0 0 0 23 0 12 12 12 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Q
% Arg: 45 12 12 12 45 0 0 0 0 12 12 0 0 12 0 % R
% Ser: 0 0 12 0 0 67 0 56 45 34 0 12 23 45 34 % S
% Thr: 0 0 0 0 0 0 0 12 0 0 12 12 12 0 0 % T
% Val: 0 12 34 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 12 12 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _