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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf68
All Species:
8.79
Human Site:
S291
Identified Species:
24.17
UniProt:
Q8N4H0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4H0
NP_001034484.2
392
45058
S291
S
S
S
C
L
D
S
S
Q
F
G
K
S
S
S
Chimpanzee
Pan troglodytes
XP_001138482
386
44359
S285
S
S
S
C
L
D
S
S
Q
F
G
K
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001085450
392
45205
S291
S
S
S
R
L
D
S
S
Q
F
G
K
S
S
S
Dog
Lupus familis
XP_851964
407
46522
F305
S
S
L
D
S
S
K
F
G
K
P
S
P
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3U6K5
488
56083
L324
F
E
R
C
E
E
Y
L
S
P
R
T
C
S
K
Rat
Rattus norvegicus
Q6AYJ3
398
46089
G300
S
P
P
P
L
N
S
G
H
F
R
K
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505251
166
19266
E68
E
C
Y
T
T
K
F
E
L
I
Q
L
V
H
P
Chicken
Gallus gallus
NP_001026453
204
23148
D106
T
Y
E
E
N
T
R
D
F
L
F
P
D
P
K
Frog
Xenopus laevis
NP_001089751
396
44772
G297
K
D
F
L
D
S
G
G
V
K
N
G
A
S
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
94.3
70.2
N.A.
27.4
60.7
N.A.
22.1
26
38.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.4
96.4
79.1
N.A.
41.1
71.1
N.A.
31.1
37.5
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
20
N.A.
13.3
33.3
N.A.
0
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
20
40
N.A.
0
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
12
0
34
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
12
0
12
12
34
0
12
0
0
0
0
12
0
0
% D
% Glu:
12
12
12
12
12
12
0
12
0
0
0
0
0
0
0
% E
% Phe:
12
0
12
0
0
0
12
12
12
45
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
23
12
0
34
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
12
12
0
0
23
0
45
0
0
23
% K
% Leu:
0
0
12
12
45
0
0
12
12
12
0
12
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
12
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
12
12
12
0
0
0
0
0
12
12
12
23
12
12
% P
% Gln:
0
0
0
0
0
0
0
0
34
0
12
0
0
0
0
% Q
% Arg:
0
0
12
12
0
0
12
0
0
0
23
0
0
0
0
% R
% Ser:
56
45
34
0
12
23
45
34
12
0
0
12
34
67
45
% S
% Thr:
12
0
0
12
12
12
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
0
0
0
12
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _