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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPRML All Species: 17.58
Human Site: S61 Identified Species: 48.33
UniProt: Q8N4K4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4K4 NP_981945.1 120 12312 S61 G L A P D E R S L W V S R V A
Chimpanzee Pan troglodytes XP_001134654 120 12324 S61 G L A P D E R S L W V S R V A
Rhesus Macaque Macaca mulatta XP_001115662 120 12236 S61 G L A P D E R S L W V S R V A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q3URD2 117 12330 S58 G L A P D E R S L W V S R V A
Rat Rattus norvegicus Q5BJN9 109 11773 Y52 G P D E R S L Y I M R V V Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511699 116 12177 S57 P G G P D E R S L Y I M R L V
Chicken Gallus gallus XP_418067 111 11886 Y54 A P D E R S L Y I T R V V Q I
Frog Xenopus laevis Q6GM22 112 12219 F55 I P D E R S L F I T R V V Q I
Zebra Danio Brachydanio rerio A5PLA0 114 12331 L56 L A Q D E R K L F V T R V V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99.1 N.A. N.A. 90 55 N.A. 49.1 65.8 60.8 59.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 99.1 N.A. N.A. 92.5 66.6 N.A. 63.3 76.6 71.6 72.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 6.6 N.A. 46.6 0 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 13.3 N.A. 66.6 6.6 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 45 0 0 0 0 0 0 0 0 0 0 0 45 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 34 12 56 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 34 12 56 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % F
% Gly: 56 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 0 34 0 12 0 0 0 34 % I
% Lys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % K
% Leu: 12 45 0 0 0 0 34 12 56 0 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 34 0 56 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 0 0 0 34 12 % Q
% Arg: 0 0 0 0 34 12 56 0 0 0 34 12 56 0 0 % R
% Ser: 0 0 0 0 0 34 0 56 0 0 0 45 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 23 12 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 12 45 34 45 56 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 23 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _