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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPEM1 All Species: 11.21
Human Site: S289 Identified Species: 49.33
UniProt: Q8N4L4 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4L4 NP_955371.2 309 34773 S289 S G C Y P L A S G S S T A E E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108543 309 34702 S289 S R C Y P L A S G S S T A E G
Dog Lupus familis XP_849703 312 34955 S292 S H C Y P L G S R S S N A E E
Cat Felis silvestris
Mouse Mus musculus Q5F289 310 35044 S290 S H C Y P L V S G S S A A E G
Rat Rattus norvegicus Q68FV4 504 56896 D340 V S R N L R S D A Q G Y R D H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519827 304 32163 T284 R D W M Y Q P T V G R A W E P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 89.6 71.4 N.A. 68.3 21.2 N.A. 27.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 93.1 79.8 N.A. 76.4 31.7 N.A. 37.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 86.6 73.3 N.A. 73.3 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 86.6 73.3 N.A. 73.3 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 34 0 17 0 0 34 67 0 0 % A
% Cys: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 0 0 0 17 0 0 0 0 0 17 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 84 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 0 0 0 0 17 0 50 17 17 0 0 0 34 % G
% His: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 17 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 17 67 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 0 0 0 0 0 0 0 17 0 0 0 % N
% Pro: 0 0 0 0 67 0 17 0 0 0 0 0 0 0 17 % P
% Gln: 0 0 0 0 0 17 0 0 0 17 0 0 0 0 0 % Q
% Arg: 17 17 17 0 0 17 0 0 17 0 17 0 17 0 0 % R
% Ser: 67 17 0 0 0 0 17 67 0 67 67 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 17 0 0 0 34 0 0 0 % T
% Val: 17 0 0 0 0 0 17 0 17 0 0 0 0 0 0 % V
% Trp: 0 0 17 0 0 0 0 0 0 0 0 0 17 0 0 % W
% Tyr: 0 0 0 67 17 0 0 0 0 0 0 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _