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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC44A3 All Species: 6.67
Human Site: S11 Identified Species: 12.22
UniProt: Q8N4M1 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4M1 NP_001107578.1 653 73783 S11 L G A E Y L V S A E G A P R Q
Chimpanzee Pan troglodytes XP_524772 856 95623 S214 L G A E Y L V S A E G A P R Q
Rhesus Macaque Macaca mulatta XP_001104696 886 98579 V244 C L G A E Y L V S A E R A P R
Dog Lupus familis XP_547273 698 78794 S57 G G S S T P A S A E R T P R P
Cat Felis silvestris
Mouse Mus musculus Q921V7 652 73009 A12 G A E Y L V S A E K T R Q R E
Rat Rattus norvegicus Q6AY92 604 67661
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507491 633 70568
Chicken Gallus gallus XP_422327 608 68365
Frog Xenopus laevis Q6IR74 651 72918 K11 C G S T Q N S K R D W R P L E
Zebra Danio Brachydanio rerio A5PMW0 702 79452 L32 V L F V I V I L G Y I A L G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZE7 691 76822 G11 A E S K D G E G E A Q N N R P
Honey Bee Apis mellifera XP_624708 668 75512 E11 C S G D D D D E Q R H N P T H
Nematode Worm Caenorhab. elegans Q20026 771 87293 K71 I A R F N V I K P D R L A K R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76 70.8 78.5 N.A. 81 74.4 N.A. 42.4 61.4 47.7 28.6 N.A. 31.9 35 22 N.A.
Protein Similarity: 100 76 72.2 84.8 N.A. 88.2 81.4 N.A. 61.8 75.1 67 47 N.A. 51 54.3 39.2 N.A.
P-Site Identity: 100 100 0 40 N.A. 6.6 0 N.A. 0 0 13.3 6.6 N.A. 6.6 6.6 0 N.A.
P-Site Similarity: 100 100 20 46.6 N.A. 33.3 0 N.A. 0 0 33.3 26.6 N.A. 20 13.3 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 16 8 0 0 8 8 24 16 0 24 16 0 0 % A
% Cys: 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 16 8 8 0 0 16 0 0 0 0 0 % D
% Glu: 0 8 8 16 8 0 8 8 16 24 8 0 0 0 16 % E
% Phe: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 31 16 0 0 8 0 8 8 0 16 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % H
% Ile: 8 0 0 0 8 0 16 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 8 0 0 0 16 0 8 0 0 0 8 0 % K
% Leu: 16 16 0 0 8 16 8 8 0 0 0 8 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 8 0 0 0 0 0 16 8 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 8 0 0 0 39 8 16 % P
% Gln: 0 0 0 0 8 0 0 0 8 0 8 0 8 0 16 % Q
% Arg: 0 0 8 0 0 0 0 0 8 8 16 24 0 39 16 % R
% Ser: 0 8 24 8 0 0 16 24 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 8 8 0 0 0 0 0 8 8 0 8 8 % T
% Val: 8 0 0 8 0 24 16 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 8 16 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _