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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZADH2 All Species: 16.97
Human Site: S338 Identified Species: 37.33
UniProt: Q8N4Q0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4Q0 NP_787103.1 377 40140 S338 E V D L G D L S P E G R F T G
Chimpanzee Pan troglodytes XP_512178 377 40060 S338 E V D L G D L S P E G R F T G
Rhesus Macaque Macaca mulatta XP_001090670 377 40129 S338 E V D L G D M S P E G R F T G
Dog Lupus familis XP_533369 377 40083 S338 E V D L G D L S V E G R F R G
Cat Felis silvestris
Mouse Mus musculus Q8BGC4 377 40510 A338 E V D L G H L A P D G R F I G
Rat Rattus norvegicus P97584 329 35700 V291 L T D L M N W V S E G K I R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419096 325 34893 P287 V D L G D L S P E G K F I G L
Frog Xenopus laevis NP_001085027 401 42862 S362 E V D Y G D Q S P E G R F T G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790754 223 24379 G185 Q G K H D P K G P F T G L E A
Poplar Tree Populus trichocarpa XP_002313845 634 68625 L592 S G K L K V V L D Q K R F D G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39172 345 38115 G307 V L P H I R E G K I T Y V E D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.5 90.1 N.A. 88 24.3 N.A. N.A. 69.2 72 N.A. N.A. N.A. N.A. N.A. 29.7
Protein Similarity: 100 99.7 98.1 93.3 N.A. 94.1 41.9 N.A. N.A. 78.2 82.7 N.A. N.A. N.A. N.A. N.A. 41.3
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 26.6 N.A. N.A. 0 86.6 N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 40 N.A. N.A. 0 86.6 N.A. N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 28 N.A. N.A. 26.7 N.A. N.A.
Protein Similarity: 40.8 N.A. N.A. 42.9 N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 64 0 19 46 0 0 10 10 0 0 0 10 10 % D
% Glu: 55 0 0 0 0 0 10 0 10 55 0 0 0 19 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 10 64 0 0 % F
% Gly: 0 19 0 10 55 0 0 19 0 10 64 10 0 10 64 % G
% His: 0 0 0 19 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 10 0 0 19 10 0 % I
% Lys: 0 0 19 0 10 0 10 0 10 0 19 10 0 0 0 % K
% Leu: 10 10 10 64 0 10 37 10 0 0 0 0 10 0 10 % L
% Met: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 10 0 10 55 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 64 0 19 0 % R
% Ser: 10 0 0 0 0 0 10 46 10 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 19 0 0 37 0 % T
% Val: 19 55 0 0 0 10 10 10 10 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _