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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZADH2
All Species:
20.91
Human Site:
T231
Identified Species:
46
UniProt:
Q8N4Q0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4Q0
NP_787103.1
377
40140
T231
Y
K
T
E
P
V
G
T
V
L
K
Q
E
Y
P
Chimpanzee
Pan troglodytes
XP_512178
377
40060
T231
Y
K
T
E
P
V
G
T
V
L
K
Q
E
Y
P
Rhesus Macaque
Macaca mulatta
XP_001090670
377
40129
T231
Y
K
T
E
P
V
G
T
V
L
K
Q
E
Y
P
Dog
Lupus familis
XP_533369
377
40083
T231
Y
H
T
E
H
V
S
T
V
L
K
Q
E
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGC4
377
40510
T231
Y
R
T
E
P
V
E
T
V
L
K
Q
E
Y
P
Rat
Rattus norvegicus
P97584
329
35700
K184
E
K
V
A
Y
L
K
K
L
G
F
D
V
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419096
325
34893
V180
K
T
E
N
V
E
S
V
L
R
K
D
Y
P
E
Frog
Xenopus laevis
NP_001085027
401
42862
S255
Y
K
T
E
N
I
G
S
V
L
K
S
Q
F
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790754
223
24379
R78
E
N
L
K
D
V
L
R
S
E
Y
P
Q
G
I
Poplar Tree
Populus trichocarpa
XP_002313845
634
68625
K485
V
D
R
V
I
D
Y
K
A
E
D
I
K
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39172
345
38115
F200
V
D
L
L
K
T
K
F
G
F
D
D
A
F
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.5
90.1
N.A.
88
24.3
N.A.
N.A.
69.2
72
N.A.
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
100
99.7
98.1
93.3
N.A.
94.1
41.9
N.A.
N.A.
78.2
82.7
N.A.
N.A.
N.A.
N.A.
N.A.
41.3
P-Site Identity:
100
100
100
80
N.A.
86.6
6.6
N.A.
N.A.
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
93.3
20
N.A.
N.A.
13.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
28
N.A.
N.A.
26.7
N.A.
N.A.
Protein Similarity:
40.8
N.A.
N.A.
42.9
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
10
10
0
0
0
0
19
28
0
0
0
% D
% Glu:
19
0
10
55
0
10
10
0
0
19
0
0
46
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
10
0
0
19
10
% F
% Gly:
0
0
0
0
0
0
37
0
10
10
0
0
0
10
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
10
% I
% Lys:
10
46
0
10
10
0
19
19
0
0
64
0
10
0
0
% K
% Leu:
0
0
19
10
0
10
10
0
19
55
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
37
0
0
0
0
0
0
10
0
10
55
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
46
19
0
0
% Q
% Arg:
0
10
10
0
0
0
0
10
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
10
10
0
0
10
0
0
0
% S
% Thr:
0
10
55
0
0
10
0
46
0
0
0
0
0
10
0
% T
% Val:
19
0
10
10
10
55
0
10
55
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
55
0
0
0
10
0
10
0
0
0
10
0
10
46
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _