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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHCHD4 All Species: 34.24
Human Site: S25 Identified Species: 53.81
UniProt: Q8N4Q1 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4Q1 NP_001091972.1 142 15996 S25 E D H E T P S S A E L V A D D
Chimpanzee Pan troglodytes XP_001157417 142 15966 S25 E D H E T P S S A E L V A D D
Rhesus Macaque Macaca mulatta XP_001091484 142 16021 N25 E D H E T P S N A E L V A D D
Dog Lupus familis XP_533726 140 15753 N25 E D H E T P S N A E L V A D D
Cat Felis silvestris
Mouse Mus musculus Q8VEA4 139 15506 S25 E D H E T P S S A E L V A D D
Rat Rattus norvegicus Q5BJN5 139 15448 S25 E D H E T P S S A E L V A D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507347 229 25495 S25 E D H E T P S S A E L V A D D
Chicken Gallus gallus NP_001107231 138 15445 S25 E D H E T P S S A E L V A D D
Frog Xenopus laevis Q63ZK1 139 15736 S25 E D H E T P S S A E L I A D D
Zebra Danio Brachydanio rerio Q6DEI8 146 15737 N25 E D H E A P S N A E L V E D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651770 158 16693 T27 E D H A T P S T I E L P P P E
Honey Bee Apis mellifera XP_001122082 156 17192 K25 E D H A T P S K I D L P E P E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787579 143 16032 K25 E D H E T P I K E E L K Y L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36046 403 44518 S239 D N N G E E E S S K K T V S D
Red Bread Mold Neurospora crassa Q7S3S2 298 31569 T79 E L P E T A G T A P S Q L T D
Conservation
Percent
Protein Identity: 100 99.3 97.8 91.5 N.A. 86.6 87.3 N.A. 51.5 84.5 79.5 68.4 N.A. 44.2 46.7 N.A. 58
Protein Similarity: 100 99.3 98.5 95.7 N.A. 90.8 91.5 N.A. 59.3 91.5 91.5 77.4 N.A. 58.2 64 N.A. 70.6
P-Site Identity: 100 100 93.3 93.3 N.A. 100 100 N.A. 100 100 93.3 80 N.A. 53.3 46.6 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 86.6 N.A. 66.6 60 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.3 26.1
Protein Similarity: N.A. N.A. N.A. N.A. 28 36.2
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 7 7 0 0 74 0 0 0 60 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 87 0 0 0 0 0 0 0 7 0 0 0 67 80 % D
% Glu: 94 0 0 80 7 7 7 0 7 80 0 0 14 0 14 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % G
% His: 0 0 87 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 14 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 14 0 7 7 7 0 0 0 % K
% Leu: 0 7 0 0 0 0 0 0 0 0 87 0 7 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 0 0 87 0 0 0 7 0 14 7 14 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 80 54 7 0 7 0 0 7 0 % S
% Thr: 0 0 0 0 87 0 0 14 0 0 0 7 0 7 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 60 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _