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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBR4 All Species: 30.61
Human Site: T186 Identified Species: 74.81
UniProt: Q8N4T8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4T8 NP_116172.2 237 25301 T186 G F V H T D M T K D L K E E H
Chimpanzee Pan troglodytes XP_526726 193 20461 K152 Q S V Y S A S K G G L V G F S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534547 237 25404 T186 G F V H T D M T K D L K E E H
Cat Felis silvestris
Mouse Mus musculus Q91VT4 236 25396 T185 G F I R T D M T R H L K E E H
Rat Rattus norvegicus Q7TS56 236 25268 T185 G F I H T D M T K H L K E E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508580 199 21638 T148 G F V H T D M T A D L K E D Y
Chicken Gallus gallus XP_420403 237 25135 T186 G F I H T E M T A H L E E D E
Frog Xenopus laevis Q6NUE2 236 25189 T185 G F I R T D M T S D L K E D S
Zebra Danio Brachydanio rerio Q6P0H7 237 24860 T186 G L I H T D M T A G L A E E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P33207 319 33530 T264 G F I A S D M T A E L G E D M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.7 N.A. 92.4 N.A. 86 84.3 N.A. 72.5 72.5 67.9 63.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 79.3 N.A. 98.3 N.A. 94 92.8 N.A. 79.3 88.6 86.5 81 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 N.A. 100 N.A. 73.3 86.6 N.A. 80 53.3 66.6 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 N.A. 100 N.A. 86.6 93.3 N.A. 93.3 80 80 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 0 0 40 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 80 0 0 0 40 0 0 0 40 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 10 0 10 90 50 10 % E
% Phe: 0 80 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 90 0 0 0 0 0 0 0 10 20 0 10 10 0 0 % G
% His: 0 0 0 60 0 0 0 0 0 30 0 0 0 0 40 % H
% Ile: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 30 0 0 60 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 100 0 0 0 0 % L
% Met: 0 0 0 0 0 0 90 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 20 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 20 0 10 0 10 0 0 0 0 0 20 % S
% Thr: 0 0 0 0 80 0 0 90 0 0 0 0 0 0 0 % T
% Val: 0 0 40 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _