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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCP11L2
All Species:
20
Human Site:
S270
Identified Species:
48.89
UniProt:
Q8N4U5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4U5
NP_689985.1
519
58091
S270
T
T
E
W
I
K
E
S
V
N
E
E
L
F
S
Chimpanzee
Pan troglodytes
XP_509333
519
58015
S270
T
T
E
W
I
K
E
S
V
N
E
E
L
F
S
Rhesus Macaque
Macaca mulatta
XP_001099194
519
57967
S270
T
T
E
W
I
K
E
S
V
N
E
E
L
F
S
Dog
Lupus familis
XP_531761
518
57919
S270
T
T
E
W
I
K
E
S
V
N
E
E
L
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1H7
517
57871
K268
S
Q
T
T
E
W
L
K
E
S
I
D
K
E
L
Rat
Rattus norvegicus
Q568Z0
517
57962
K268
S
Q
T
T
E
W
L
K
E
S
I
D
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508335
518
58077
E269
Q
T
T
E
W
I
K
E
S
V
N
E
L
L
S
Chicken
Gallus gallus
NP_001001897
509
56877
S262
T
T
E
W
I
K
E
S
I
E
D
E
L
S
S
Frog
Xenopus laevis
NP_001086254
504
56545
E265
I
V
T
K
W
L
Q
E
V
A
D
T
L
A
P
Zebra Danio
Brachydanio rerio
NP_998185
529
59080
S276
T
T
E
W
I
K
S
S
I
E
E
A
T
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
92
N.A.
78.8
79.1
N.A.
82
71.6
39.6
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98
96.3
N.A.
90.1
89.5
N.A.
90.1
84.5
59.9
69.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
26.6
73.3
13.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
33.3
86.6
26.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
20
20
0
0
0
% D
% Glu:
0
0
60
10
20
0
50
20
20
20
50
60
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
60
10
0
0
20
0
20
0
0
0
10
% I
% Lys:
0
0
0
10
0
60
10
20
0
0
0
0
20
0
0
% K
% Leu:
0
0
0
0
0
10
20
0
0
0
0
0
70
20
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
40
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
10
20
0
0
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
0
0
10
60
10
20
0
0
0
10
60
% S
% Thr:
60
70
40
20
0
0
0
0
0
0
0
10
10
0
0
% T
% Val:
0
10
0
0
0
0
0
0
50
10
0
0
0
0
0
% V
% Trp:
0
0
0
60
20
20
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _