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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SVOP All Species: 27.27
Human Site: S521 Identified Species: 54.55
UniProt: Q8N4V2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4V2 NP_061181.1 548 60769 S521 G R G L Q E S S H R E W G Q E
Chimpanzee Pan troglodytes XP_001171562 482 53513 G460 E S S H R E W G Q E M V G R G
Rhesus Macaque Macaca mulatta XP_001103835 548 60800 S521 G R G L Q E S S H R E W G Q E
Dog Lupus familis XP_543442 545 60305 S518 G R G L Q E S S H R E W G Q E
Cat Felis silvestris
Mouse Mus musculus Q8BFT9 548 60751 S521 G R A L Q E S S H R E W G Q E
Rat Rattus norvegicus Q9Z2I7 548 60786 S521 G R A L Q E S S H R E W G Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508097 618 67981 S591 G R G L Q E S S H R E W G Q E
Chicken Gallus gallus XP_415186 439 49234 A417 L G T C S G M A R V G A L I T
Frog Xenopus laevis Q2XWK0 548 60977 S521 G R G L Q E S S H R E W G Q E
Zebra Danio Brachydanio rerio Q1LVS8 506 56533 C483 L S P F A T A C I I C A I G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCA2 548 60985 A526 E N F G K K P A P Q E T A E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30638 520 57184 S487 V A S E K S L S L P I G I Y G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 99.6 96.3 N.A. 95.6 96.1 N.A. 81.2 75.5 87.7 34.8 N.A. 23.1 N.A. 47.9 N.A.
Protein Similarity: 100 83.9 99.6 97.2 N.A. 98.1 97.9 N.A. 84.9 77.9 95.6 56.2 N.A. 44.8 N.A. 63.1 N.A.
P-Site Identity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. 100 0 100 0 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 93.3 93.3 N.A. 100 6.6 100 6.6 N.A. 46.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 0 9 0 9 17 0 0 0 17 9 0 0 % A
% Cys: 0 0 0 9 0 0 0 9 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 0 0 9 0 67 0 0 0 9 67 0 0 9 67 % E
% Phe: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 59 9 42 9 0 9 0 9 0 0 9 9 67 9 17 % G
% His: 0 0 0 9 0 0 0 0 59 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 9 0 17 9 0 % I
% Lys: 0 0 0 0 17 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 0 59 0 0 9 0 9 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 9 0 9 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 59 0 0 0 9 9 0 0 0 59 0 % Q
% Arg: 0 59 0 0 9 0 0 0 9 59 0 0 0 9 0 % R
% Ser: 0 17 17 0 9 9 59 67 0 0 0 0 0 0 0 % S
% Thr: 0 0 9 0 0 9 0 0 0 0 0 9 0 0 9 % T
% Val: 9 0 0 0 0 0 0 0 0 9 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 59 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _