KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB4A
All Species:
14.85
Human Site:
S23
Identified Species:
54.44
UniProt:
Q8N4Y2
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4Y2
NP_775855.3
294
32746
S23
E
G
E
L
E
G
G
S
A
G
P
R
A
A
I
Chimpanzee
Pan troglodytes
XP_001156341
349
40105
T45
Q
K
E
T
Q
E
Q
T
S
G
Q
L
V
M
L
Rhesus Macaque
Macaca mulatta
XP_001088585
297
33324
S23
E
G
E
L
E
G
G
S
A
G
P
Q
A
A
M
Dog
Lupus familis
XP_854171
411
46818
S31
E
E
V
E
E
A
G
S
V
R
P
R
A
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZJ8
394
44419
T18
E
G
Q
E
G
E
E
T
T
G
V
S
A
R
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421040
513
59963
S28
D
E
E
D
D
V
A
S
G
A
S
P
S
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B3DGU2
502
57890
S71
H
F
E
I
S
D
Q
S
A
L
S
S
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.5
92.9
55.7
N.A.
54
N.A.
N.A.
N.A.
25.7
N.A.
20.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
47.8
95.6
60.8
N.A.
59.6
N.A.
N.A.
N.A.
38.4
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
86.6
46.6
N.A.
26.6
N.A.
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
53.3
N.A.
40
N.A.
N.A.
N.A.
40
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
15
0
43
15
0
0
72
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
15
15
15
0
0
0
0
0
0
0
0
0
% D
% Glu:
58
29
72
29
43
29
15
0
0
0
0
0
0
15
0
% E
% Phe:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
43
0
0
15
29
43
0
15
58
0
0
0
0
0
% G
% His:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% H
% Ile:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
29
0
0
0
0
0
15
0
15
0
0
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
29
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
43
15
0
0
0
% P
% Gln:
15
0
15
0
15
0
29
0
0
0
15
15
0
0
15
% Q
% Arg:
0
0
0
0
0
0
0
0
0
15
0
29
0
15
0
% R
% Ser:
0
0
0
0
15
0
0
72
15
0
29
29
15
29
0
% S
% Thr:
0
0
0
15
0
0
0
29
15
0
0
0
0
0
0
% T
% Val:
0
0
15
0
0
15
0
0
15
0
15
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _