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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MREG All Species: 26.67
Human Site: T96 Identified Species: 73.33
UniProt: Q8N565 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N565 NP_060470.2 214 24927 T96 K L N Y D I H T L R Q V R R E
Chimpanzee Pan troglodytes XP_516074 331 37801 T203 K L N Y D I H T L R Q V R R E
Rhesus Macaque Macaca mulatta XP_001085687 214 25005 T96 K L N Y D I H T L R Q V R R E
Dog Lupus familis XP_852765 240 27961 T122 K L N Y D I Y T L R Q I R R E
Cat Felis silvestris
Mouse Mus musculus Q6NVG5 214 24991 T96 R L N Y D I Y T L R Q I R R E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508484 129 15064 E35 E D L G F Q K E A D S L L S V
Chicken Gallus gallus XP_421870 215 24318 T102 K L N Y D I Y T L R Q T R K E
Frog Xenopus laevis NP_001090039 202 23816 T93 K L N Y E I Y T L R Q A R R E
Zebra Danio Brachydanio rerio Q6GQM0 234 27131 A96 R L S I D I E A M R D V R R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.2 97.6 74.5 N.A. 85.9 N.A. N.A. 46.7 71.1 50.9 41 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 62.5 98.5 79.1 N.A. 92 N.A. N.A. 51.4 81.4 65.8 54.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 N.A. N.A. 0 80 80 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 13.3 93.3 93.3 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 12 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 78 0 0 0 0 12 12 0 0 0 0 % D
% Glu: 12 0 0 0 12 0 12 12 0 0 0 0 0 0 89 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 89 0 0 0 0 0 23 0 0 0 % I
% Lys: 67 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % K
% Leu: 0 89 12 0 0 0 0 0 78 0 0 12 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 78 0 0 0 0 % Q
% Arg: 23 0 0 0 0 0 0 0 0 89 0 0 89 78 0 % R
% Ser: 0 0 12 0 0 0 0 0 0 0 12 0 0 12 0 % S
% Thr: 0 0 0 0 0 0 0 78 0 0 0 12 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 45 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 78 0 0 45 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _