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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MREG
All Species:
19.7
Human Site:
Y190
Identified Species:
54.17
UniProt:
Q8N565
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N565
NP_060470.2
214
24927
Y190
F
K
L
A
R
R
T
Y
P
K
K
P
G
V
P
Chimpanzee
Pan troglodytes
XP_516074
331
37801
Y297
F
K
L
A
R
R
T
Y
P
K
K
P
G
V
P
Rhesus Macaque
Macaca mulatta
XP_001085687
214
25005
Y190
F
K
L
A
R
R
T
Y
P
K
K
P
G
V
P
Dog
Lupus familis
XP_852765
240
27961
Y216
F
K
I
A
S
R
T
Y
P
K
K
P
G
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6NVG5
214
24991
Y190
F
K
I
A
S
Q
M
Y
P
K
K
P
G
V
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508484
129
15064
P109
S
H
A
Y
P
R
R
P
C
V
P
P
T
N
G
Chicken
Gallus gallus
XP_421870
215
24318
F188
A
L
D
A
A
D
E
F
F
K
L
A
S
V
V
Frog
Xenopus laevis
NP_001090039
202
23816
Y182
T
F
Y
W
W
L
V
Y
V
W
L
L
T
I
S
Zebra Danio
Brachydanio rerio
Q6GQM0
234
27131
Y190
V
A
K
A
R
R
F
Y
P
P
K
D
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.2
97.6
74.5
N.A.
85.9
N.A.
N.A.
46.7
71.1
50.9
41
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.5
98.5
79.1
N.A.
92
N.A.
N.A.
51.4
81.4
65.8
54.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
N.A.
N.A.
13.3
20
6.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
13.3
26.6
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
78
12
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
12
0
0
0
0
0
12
12
12
0
% D
% Glu:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% E
% Phe:
56
12
0
0
0
0
12
12
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
56
0
12
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
0
0
0
0
0
0
0
0
0
0
23
0
% I
% Lys:
0
56
12
0
0
0
0
0
0
67
67
0
0
0
0
% K
% Leu:
0
12
34
0
0
12
0
0
0
0
23
12
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
12
0
0
12
67
12
12
67
0
0
56
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
45
67
12
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
23
0
0
0
0
0
0
0
12
0
12
% S
% Thr:
12
0
0
0
0
0
45
0
0
0
0
0
23
0
0
% T
% Val:
12
0
0
0
0
0
12
0
12
12
0
0
0
56
12
% V
% Trp:
0
0
0
12
12
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
12
12
0
0
0
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _