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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZCCHC9 All Species: 27.27
Human Site: S218 Identified Species: 50
UniProt: Q8N567 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N567 NP_001124507.1 271 30477 S218 G G C K L C G S V E H L K K D
Chimpanzee Pan troglodytes XP_001149522 271 30417 S218 G G C K L C G S V E H L K K D
Rhesus Macaque Macaca mulatta XP_001110934 270 30213 S217 G G C K L C G S V E H L K K D
Dog Lupus familis XP_536305 271 30478 S218 G C C R L C G S V E H F K K D
Cat Felis silvestris
Mouse Mus musculus Q8R1J3 273 30746 S218 G S C K L C G S V E H F K K D
Rat Rattus norvegicus P62634 177 19444 F125 K C Y S C G E F G H I Q K D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509827 270 30484 S217 G C C R L C G S V E H F K K D
Chicken Gallus gallus O42395 172 19025 F120 K C Y S C G E F G H I Q K D C
Frog Xenopus laevis NP_001084565 248 27993 S195 G S C R I C G S V E H F Q R D
Zebra Danio Brachydanio rerio NP_938184 256 28388 V202 A A G G C C R V C G S V E H F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121478 382 44425 S301 G I C Y K C G S T E H T H F E
Nematode Worm Caenorhab. elegans NP_494168 384 42992 A314 G C C N V C G A N T H L R R D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002322472 278 31249 G188 G C C K L C G G V T H L A R D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.7 92.9 N.A. 82.7 20.6 N.A. 76 20.6 56.8 52 N.A. N.A. 22.5 28.6 N.A.
Protein Similarity: 100 100 98.1 96.6 N.A. 92.6 33.9 N.A. 86.7 32.8 66.7 68.6 N.A. N.A. 36.1 42.4 N.A.
P-Site Identity: 100 100 100 80 N.A. 86.6 6.6 N.A. 80 6.6 60 6.6 N.A. N.A. 46.6 46.6 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 6.6 N.A. 86.6 6.6 86.6 20 N.A. N.A. 53.3 73.3 N.A.
Percent
Protein Identity: 20.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 73.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 8 0 0 0 0 8 0 0 % A
% Cys: 0 47 77 0 24 85 0 0 8 0 0 0 0 0 16 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 70 % D
% Glu: 0 0 0 0 0 0 16 0 0 62 0 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 31 0 8 8 % F
% Gly: 77 24 8 8 0 16 77 8 16 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 16 77 0 8 8 0 % H
% Ile: 0 8 0 0 8 0 0 0 0 0 16 0 0 0 0 % I
% Lys: 16 0 0 39 8 0 0 0 0 0 0 0 62 47 0 % K
% Leu: 0 0 0 0 54 0 0 0 0 0 0 39 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 16 8 0 0 % Q
% Arg: 0 0 0 24 0 0 8 0 0 0 0 0 8 24 0 % R
% Ser: 0 16 0 16 0 0 0 62 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 16 0 8 0 0 0 % T
% Val: 0 0 0 0 8 0 0 8 62 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _