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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK2
All Species:
23.03
Human Site:
Y394
Identified Species:
50.67
UniProt:
Q8N568
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N568
NP_001035350.2
766
83612
Y394
S
S
T
L
L
E
K
Y
K
I
G
K
V
I
G
Chimpanzee
Pan troglodytes
XP_001150968
766
83601
Y394
S
S
T
L
L
E
K
Y
K
I
G
K
V
I
G
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
Y411
S
S
T
L
L
E
K
Y
K
I
G
K
V
I
G
Dog
Lupus familis
XP_539760
862
93767
Y411
S
S
T
L
L
E
K
Y
K
I
G
K
V
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGN3
756
82960
Y393
S
F
P
L
L
E
K
Y
R
I
G
K
V
I
G
Rat
Rattus norvegicus
Q5MPA9
767
83998
Y409
S
F
T
L
L
E
K
Y
R
I
G
K
V
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511279
630
68724
C294
K
I
I
D
K
A
K
C
C
G
K
E
H
L
I
Chicken
Gallus gallus
XP_420439
761
82932
K392
S
T
I
L
E
K
Y
K
V
G
K
V
I
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139259
791
87409
D399
L
A
A
S
T
I
L
D
K
Y
K
I
G
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394386
670
74883
V334
I
G
E
G
N
F
A
V
V
R
H
C
S
H
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
S325
S
P
T
A
T
R
R
S
P
L
A
N
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
81.9
N.A.
93.4
92.6
N.A.
71
84.5
N.A.
71.5
N.A.
N.A.
39.5
N.A.
48.6
Protein Similarity:
100
99.4
97
83.9
N.A.
95.4
95
N.A.
75.7
89.9
N.A.
82.4
N.A.
N.A.
57
N.A.
62.1
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
6.6
13.3
N.A.
6.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
20
33.3
N.A.
13.3
N.A.
N.A.
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
10
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
10
55
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
19
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
0
0
0
0
19
55
0
10
10
55
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% H
% Ile:
10
10
19
0
0
10
0
0
0
55
0
10
10
55
10
% I
% Lys:
10
0
0
0
10
10
64
10
46
0
28
55
0
10
10
% K
% Leu:
10
0
0
64
55
0
10
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
10
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
0
19
10
0
0
0
0
0
% R
% Ser:
73
37
0
10
0
0
0
10
0
0
0
0
10
0
10
% S
% Thr:
0
10
55
0
19
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
19
0
0
10
55
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
55
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _