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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK2
All Species:
20.61
Human Site:
Y497
Identified Species:
45.33
UniProt:
Q8N568
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N568
NP_001035350.2
766
83612
Y497
R
D
G
S
A
M
V
Y
N
L
A
N
A
L
R
Chimpanzee
Pan troglodytes
XP_001150968
766
83601
Y497
R
D
G
S
A
M
V
Y
N
L
A
N
A
L
R
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
Y514
R
D
G
S
A
M
V
Y
N
L
A
N
A
L
R
Dog
Lupus familis
XP_539760
862
93767
F514
R
D
G
S
A
M
V
F
N
L
A
N
A
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGN3
756
82960
Y496
R
D
G
S
A
M
V
Y
N
L
A
N
A
L
R
Rat
Rattus norvegicus
Q5MPA9
767
83998
S508
K
Y
T
E
R
D
G
S
A
M
V
Y
N
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511279
630
68724
S372
S
A
L
K
Y
L
H
S
L
N
I
V
H
R
D
Chicken
Gallus gallus
XP_420439
761
82932
Y494
R
D
G
S
A
M
V
Y
N
L
A
S
A
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139259
791
87409
F504
K
D
A
S
V
M
V
F
D
L
A
A
A
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394386
670
74883
T412
F
D
A
I
A
A
A
T
K
F
S
E
S
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
K403
D
G
N
F
A
V
V
K
E
C
K
N
R
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.4
81.9
N.A.
93.4
92.6
N.A.
71
84.5
N.A.
71.5
N.A.
N.A.
39.5
N.A.
48.6
Protein Similarity:
100
99.4
97
83.9
N.A.
95.4
95
N.A.
75.7
89.9
N.A.
82.4
N.A.
N.A.
57
N.A.
62.1
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
0
86.6
N.A.
53.3
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
6.6
100
N.A.
80
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
0
73
10
10
0
10
0
64
10
64
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
73
0
0
0
10
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
0
10
0
0
0
0
10
0
0
10
0
10
0
% E
% Phe:
10
0
0
10
0
0
0
19
0
10
0
0
0
0
0
% F
% Gly:
0
10
55
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
19
0
0
10
0
0
0
10
10
0
10
0
0
0
19
% K
% Leu:
0
0
10
0
0
10
0
0
10
64
0
0
0
73
0
% L
% Met:
0
0
0
0
0
64
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
55
10
0
55
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
55
0
0
0
10
0
0
0
0
0
0
0
10
10
46
% R
% Ser:
10
0
0
64
0
0
0
19
0
0
10
10
10
10
0
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
10
10
73
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
46
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _