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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC39C All Species: 13.33
Human Site: S220 Identified Species: 26.67
UniProt: Q8N584 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N584 NP_001129465.1 583 65870 S220 N R L K G A V S F G Y G L F H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095756 522 59195 S195 D R L Q G L S S L M Y A S E S
Dog Lupus familis XP_537296 319 36594
Cat Felis silvestris
Mouse Mus musculus Q8VE09 580 65427 S217 S R L K G A V S F G Y G L F H
Rat Rattus norvegicus Q0VGK2 522 58959 S195 D R L Q G L S S L T Y A S E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505723 546 61912 K202 M V P P N L L K I I N L L G F
Chicken Gallus gallus XP_419163 576 65068 S213 N R L K G A V S F G Y G L F H
Frog Xenopus laevis Q5XHH9 586 66802 A206 G V K L G I G A F N L M L S L
Zebra Danio Brachydanio rerio Q1LXE6 579 65154 K212 D E V L D R L K G S V S F G Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623336 526 60145 F199 R L M S A V S F G Y G I Y Q L
Nematode Worm Caenorhab. elegans Q09266 578 66748 R205 E Q F E S G T R M G L G T F S
Sea Urchin Strong. purpuratus XP_798627 566 63716 G202 A L A R L K G G V S F G Y G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 89.1 54 N.A. 94 84.3 N.A. 86.4 89.3 26.9 72.7 N.A. N.A. 35.6 22.2 48
Protein Similarity: 100 N.A. 89.1 54.3 N.A. 96.9 87.1 N.A. 90.3 93.8 48.6 85.5 N.A. N.A. 58.6 43.4 68.7
P-Site Identity: 100 N.A. 33.3 0 N.A. 93.3 33.3 N.A. 6.6 100 20 0 N.A. N.A. 0 20 6.6
P-Site Similarity: 100 N.A. 46.6 0 N.A. 100 46.6 N.A. 13.3 100 26.6 26.6 N.A. N.A. 6.6 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 9 25 0 9 0 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 9 0 9 0 0 0 0 0 0 0 0 0 17 0 % E
% Phe: 0 0 9 0 0 0 0 9 34 0 9 0 9 34 9 % F
% Gly: 9 0 0 0 50 9 17 9 17 34 9 42 0 25 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % H
% Ile: 0 0 0 0 0 9 0 0 9 9 0 9 0 0 0 % I
% Lys: 0 0 9 25 0 9 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 17 42 17 9 25 17 0 17 0 17 9 42 0 25 % L
% Met: 9 0 9 0 0 0 0 0 9 9 0 9 0 0 0 % M
% Asn: 17 0 0 0 9 0 0 0 0 9 9 0 0 0 0 % N
% Pro: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 17 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 9 42 0 9 0 9 0 9 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 9 9 0 25 42 0 17 0 9 17 9 25 % S
% Thr: 0 0 0 0 0 0 9 0 0 9 0 0 9 0 0 % T
% Val: 0 17 9 0 0 9 25 0 9 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 42 0 17 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _