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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC39C All Species: 11.52
Human Site: T188 Identified Species: 23.03
UniProt: Q8N584 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N584 NP_001129465.1 583 65870 T188 E L Y Q K K L T E E S L T S D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095756 522 59195 G163 G A V S F G Y G L F H L C I S
Dog Lupus familis XP_537296 319 36594
Cat Felis silvestris
Mouse Mus musculus Q8VE09 580 65427 T185 E L Y Q K K L T E E P L A S D
Rat Rattus norvegicus Q0VGK2 522 58959 G163 G A V S F G Y G L F H L C I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505723 546 61912 V170 N H I A A E G V S E E T L N R
Chicken Gallus gallus XP_419163 576 65068 T181 E I Y Q K K T T Q E S L T S D
Frog Xenopus laevis Q5XHH9 586 66802 E174 T S Y Q I Y K E C H Q M Y S L
Zebra Danio Brachydanio rerio Q1LXE6 579 65154 S180 E A C R R R S S D Q Q G A L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623336 526 60145 K167 K S Q K R I T K E I I R K N N
Nematode Worm Caenorhab. elegans Q09266 578 66748 Y173 A L N I R T C Y Q T Y R Y C E
Sea Urchin Strong. purpuratus XP_798627 566 63716 E170 E A R G E K M E E T P E M L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 89.1 54 N.A. 94 84.3 N.A. 86.4 89.3 26.9 72.7 N.A. N.A. 35.6 22.2 48
Protein Similarity: 100 N.A. 89.1 54.3 N.A. 96.9 87.1 N.A. 90.3 93.8 48.6 85.5 N.A. N.A. 58.6 43.4 68.7
P-Site Identity: 100 N.A. 6.6 0 N.A. 86.6 6.6 N.A. 6.6 80 20 6.6 N.A. N.A. 6.6 6.6 20
P-Site Similarity: 100 N.A. 6.6 0 N.A. 86.6 6.6 N.A. 20 93.3 26.6 46.6 N.A. N.A. 40 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 34 0 9 9 0 0 0 0 0 0 0 17 0 9 % A
% Cys: 0 0 9 0 0 0 9 0 9 0 0 0 17 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 25 % D
% Glu: 42 0 0 0 9 9 0 17 34 34 9 9 0 0 9 % E
% Phe: 0 0 0 0 17 0 0 0 0 17 0 0 0 0 0 % F
% Gly: 17 0 0 9 0 17 9 17 0 0 0 9 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 9 17 0 0 0 0 % H
% Ile: 0 9 9 9 9 9 0 0 0 9 9 0 0 17 0 % I
% Lys: 9 0 0 9 25 34 9 9 0 0 0 0 9 0 0 % K
% Leu: 0 25 0 0 0 0 17 0 17 0 0 42 9 17 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 9 9 0 0 % M
% Asn: 9 0 9 0 0 0 0 0 0 0 0 0 0 17 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % P
% Gln: 0 0 9 34 0 0 0 0 17 9 17 0 0 0 0 % Q
% Arg: 0 0 9 9 25 9 0 0 0 0 0 17 0 0 9 % R
% Ser: 0 17 0 17 0 0 9 9 9 0 17 0 0 34 17 % S
% Thr: 9 0 0 0 0 9 17 25 0 17 0 9 17 0 0 % T
% Val: 0 0 17 0 0 0 0 9 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 34 0 0 9 17 9 0 0 9 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _