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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC39C All Species: 15.45
Human Site: Y259 Identified Species: 30.91
UniProt: Q8N584 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N584 NP_001129465.1 583 65870 Y259 Q G L S S L M Y A S E S K D M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095756 522 59195 F225 H T V V R P F F A L D G S D N
Dog Lupus familis XP_537296 319 36594 F22 H T V V R P F F A L D G S D N
Cat Felis silvestris
Mouse Mus musculus Q8VE09 580 65427 Y256 Q G L S S L T Y A S E S K D M
Rat Rattus norvegicus Q0VGK2 522 58959 F225 H T V V R P F F A L D G S D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505723 546 61912 P232 E S K D M K A P L A T L A L L
Chicken Gallus gallus XP_419163 576 65068 Y252 Q G L S S L M Y A S E S K D M
Frog Xenopus laevis Q5XHH9 586 66802 E240 L G L S Q L R E G A S G S S I
Zebra Danio Brachydanio rerio Q1LXE6 579 65154 Y255 Q G L A S L A Y A S E S K D M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623336 526 60145 E229 L G F E G D R E A G L T A L M
Nematode Worm Caenorhab. elegans Q09266 578 66748 V245 G M R D L H H V A S M T G T L
Sea Urchin Strong. purpuratus XP_798627 566 63716 T243 F G L K C L D T A S H S T D M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 89.1 54 N.A. 94 84.3 N.A. 86.4 89.3 26.9 72.7 N.A. N.A. 35.6 22.2 48
Protein Similarity: 100 N.A. 89.1 54.3 N.A. 96.9 87.1 N.A. 90.3 93.8 48.6 85.5 N.A. N.A. 58.6 43.4 68.7
P-Site Identity: 100 N.A. 13.3 13.3 N.A. 93.3 13.3 N.A. 0 100 26.6 86.6 N.A. N.A. 20 13.3 53.3
P-Site Similarity: 100 N.A. 33.3 33.3 N.A. 93.3 33.3 N.A. 20 100 40 93.3 N.A. N.A. 26.6 26.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 17 0 84 17 0 0 17 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 0 9 9 0 0 0 25 0 0 67 0 % D
% Glu: 9 0 0 9 0 0 0 17 0 0 34 0 0 0 0 % E
% Phe: 9 0 9 0 0 0 25 25 0 0 0 0 0 0 0 % F
% Gly: 9 59 0 0 9 0 0 0 9 9 0 34 9 0 0 % G
% His: 25 0 0 0 0 9 9 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 9 9 0 9 0 0 0 0 0 0 34 0 0 % K
% Leu: 17 0 50 0 9 50 0 0 9 25 9 9 0 17 17 % L
% Met: 0 9 0 0 9 0 17 0 0 0 9 0 0 0 50 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % N
% Pro: 0 0 0 0 0 25 0 9 0 0 0 0 0 0 0 % P
% Gln: 34 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 25 0 17 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 34 34 0 0 0 0 50 9 42 34 9 0 % S
% Thr: 0 25 0 0 0 0 9 9 0 0 9 17 9 9 0 % T
% Val: 0 0 25 25 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _