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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC39C All Species: 21.82
Human Site: Y527 Identified Species: 43.64
UniProt: Q8N584 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N584 NP_001129465.1 583 65870 Y527 N N L Y V Q P Y A C Y E L G C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095756 522 59195 Y469 Y V Q P Y A C Y E L G C L L L
Dog Lupus familis XP_537296 319 36594 Y266 Y V Q P Y A C Y E L G C L L L
Cat Felis silvestris
Mouse Mus musculus Q8VE09 580 65427 Y524 S N S Y V P P Y A C Y E L G C
Rat Rattus norvegicus Q0VGK2 522 58959 Y469 Y V Q P Y A C Y E L G C L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505723 546 61912 Y490 N N L Y I Q P Y A C Y E L G C
Chicken Gallus gallus XP_419163 576 65068 Y520 N N L Y I Q P Y A C Y E L G C
Frog Xenopus laevis Q5XHH9 586 66802 F525 Y D H Y L I P F T F Y E L G L
Zebra Danio Brachydanio rerio Q1LXE6 579 65154 Y523 N N S Y V Q P Y A C Y E L G C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623336 526 60145 L473 P M A G L A N L I E G A A Y S
Nematode Worm Caenorhab. elegans Q09266 578 66748 N523 S F T Y L P P N A T Y E L A M
Sea Urchin Strong. purpuratus XP_798627 566 63716 Y512 P E A H A A P Y A C F E L G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 89.1 54 N.A. 94 84.3 N.A. 86.4 89.3 26.9 72.7 N.A. N.A. 35.6 22.2 48
Protein Similarity: 100 N.A. 89.1 54.3 N.A. 96.9 87.1 N.A. 90.3 93.8 48.6 85.5 N.A. N.A. 58.6 43.4 68.7
P-Site Identity: 100 N.A. 13.3 13.3 N.A. 80 13.3 N.A. 93.3 93.3 40 93.3 N.A. N.A. 0 40 46.6
P-Site Similarity: 100 N.A. 13.3 13.3 N.A. 86.6 13.3 N.A. 100 100 60 93.3 N.A. N.A. 6.6 53.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 9 42 0 0 59 0 0 9 9 9 9 % A
% Cys: 0 0 0 0 0 0 25 0 0 50 0 25 0 0 42 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 0 25 9 0 67 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 9 0 9 9 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 34 0 0 59 0 % G
% His: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 17 9 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 25 0 25 0 0 9 0 25 0 0 92 25 34 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 34 42 0 0 0 0 9 9 0 0 0 0 0 0 0 % N
% Pro: 17 0 0 25 0 17 67 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 25 0 0 34 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 0 17 0 0 0 0 0 0 0 0 0 0 0 9 % S
% Thr: 0 0 9 0 0 0 0 0 9 9 0 0 0 0 0 % T
% Val: 0 25 0 0 25 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 34 0 0 59 25 0 0 75 0 0 59 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _