KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTWD1
All Species:
1.21
Human Site:
S16
Identified Species:
2.42
UniProt:
Q8N5C7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5C7
NP_001138427.1
304
35248
S16
L
K
R
S
E
E
N
S
S
K
F
V
E
T
K
Chimpanzee
Pan troglodytes
XP_510391
226
25925
Rhesus Macaque
Macaca mulatta
XP_001113941
304
35284
N16
L
K
R
S
E
E
N
N
S
K
F
V
E
T
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U7
304
34716
N16
P
Q
E
S
K
E
D
N
A
N
C
V
E
T
K
Rat
Rattus norvegicus
Q6AYF5
304
34884
N16
P
Q
E
S
E
E
N
N
A
N
C
V
E
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520515
304
34841
F17
G
Q
Q
N
E
E
A
F
L
R
E
R
E
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DDV1
291
33524
F16
E
K
K
D
S
S
S
F
K
S
F
H
D
G
A
Zebra Danio
Brachydanio rerio
Q5XJ56
251
28410
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651693
327
37834
F16
Q
R
S
R
K
Y
P
F
V
H
M
R
I
A
D
Honey Bee
Apis mellifera
XP_624367
267
31856
Nematode Worm
Caenorhab. elegans
NP_496093
557
63487
S112
V
R
T
R
L
I
R
S
F
I
P
R
K
P
S
Sea Urchin
Strong. purpuratus
XP_787673
347
40065
R34
A
L
V
A
L
K
Q
R
S
K
C
S
E
C
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
98
N.A.
N.A.
73.6
75.3
N.A.
64.8
N.A.
55.5
47
N.A.
34.8
39.1
21.3
29.1
Protein Similarity:
100
74.3
99
N.A.
N.A.
86.5
85.1
N.A.
77.6
N.A.
71
60.8
N.A.
54.1
57.2
32.3
46.6
P-Site Identity:
100
0
93.3
N.A.
N.A.
40
53.3
N.A.
20
N.A.
13.3
0
N.A.
0
0
6.6
20
P-Site Similarity:
100
0
100
N.A.
N.A.
73.3
73.3
N.A.
60
N.A.
33.3
0
N.A.
13.3
0
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
9
0
17
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
25
0
0
9
0
% C
% Asp:
0
0
0
9
0
0
9
0
0
0
0
0
9
0
9
% D
% Glu:
9
0
17
0
34
42
0
0
0
0
9
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
25
9
0
25
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
9
0
0
9
0
0
% I
% Lys:
0
25
9
0
17
9
0
0
9
25
0
0
9
0
34
% K
% Leu:
17
9
0
0
17
0
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
25
25
0
17
0
0
0
0
0
% N
% Pro:
17
0
0
0
0
0
9
0
0
0
9
0
0
9
0
% P
% Gln:
9
25
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
17
17
0
0
9
9
0
9
0
25
0
0
17
% R
% Ser:
0
0
9
34
9
9
9
17
25
9
0
9
0
9
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
34
0
% T
% Val:
9
0
9
0
0
0
0
0
9
0
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _