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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTWD1 All Species: 13.03
Human Site: S53 Identified Species: 26.06
UniProt: Q8N5C7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5C7 NP_001138427.1 304 35248 S53 V L Q K A Q Q S G R S K C L K
Chimpanzee Pan troglodytes XP_510391 226 25925
Rhesus Macaque Macaca mulatta XP_001113941 304 35284 S53 V L Q K A Q Q S G R S K C L R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9D8U7 304 34716 S53 V L R K A Q Q S G R S R C R Q
Rat Rattus norvegicus Q6AYF5 304 34884 S53 V L H K A Q Q S G R S R C L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520515 304 34841 A54 R A Q G R G R A R C P R C R S
Chicken Gallus gallus
Frog Xenopus laevis Q6DDV1 291 33524 P53 K K G R S K C P K C N S S R M
Zebra Danio Brachydanio rerio Q5XJ56 251 28410 L23 K I A S H A P L D D A Q R A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651693 327 37834 P53 F C Y S C C V P V G E L E E L
Honey Bee Apis mellifera XP_624367 267 31856 L39 K I T N A R I L D T I E G R E
Nematode Worm Caenorhab. elegans NP_496093 557 63487 G149 L Y N M K T S G I V I Q N G T
Sea Urchin Strong. purpuratus XP_787673 347 40065 V71 I V K L P V K V D V I K H S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.3 98 N.A. N.A. 73.6 75.3 N.A. 64.8 N.A. 55.5 47 N.A. 34.8 39.1 21.3 29.1
Protein Similarity: 100 74.3 99 N.A. N.A. 86.5 85.1 N.A. 77.6 N.A. 71 60.8 N.A. 54.1 57.2 32.3 46.6
P-Site Identity: 100 0 93.3 N.A. N.A. 73.3 80 N.A. 13.3 N.A. 0 0 N.A. 0 6.6 0 6.6
P-Site Similarity: 100 0 100 N.A. N.A. 93.3 93.3 N.A. 33.3 N.A. 26.6 20 N.A. 0 33.3 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 42 9 0 9 0 0 9 0 0 9 0 % A
% Cys: 0 9 0 0 9 9 9 0 0 17 0 0 42 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 25 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 9 9 9 9 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 9 0 9 0 9 34 9 0 0 9 9 9 % G
% His: 0 0 9 0 9 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 17 0 0 0 0 9 0 9 0 25 0 0 0 0 % I
% Lys: 25 9 9 34 9 9 9 0 9 0 0 25 0 0 9 % K
% Leu: 9 34 0 9 0 0 0 17 0 0 0 9 0 25 9 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 9 9 0 0 0 0 0 0 9 0 9 0 0 % N
% Pro: 0 0 0 0 9 0 9 17 0 0 9 0 0 0 0 % P
% Gln: 0 0 25 0 0 34 34 0 0 0 0 17 0 0 17 % Q
% Arg: 9 0 9 9 9 9 9 0 9 34 0 25 9 34 17 % R
% Ser: 0 0 0 17 9 0 9 34 0 0 34 9 9 9 9 % S
% Thr: 0 0 9 0 0 9 0 0 0 9 0 0 0 0 9 % T
% Val: 34 9 0 0 0 9 9 9 9 17 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _