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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTWD1
All Species:
9.39
Human Site:
T181
Identified Species:
18.79
UniProt:
Q8N5C7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5C7
NP_001138427.1
304
35248
T181
P
S
F
K
R
K
R
T
E
E
Q
E
F
C
D
Chimpanzee
Pan troglodytes
XP_510391
226
25925
G104
K
H
P
N
E
T
D
G
K
S
T
A
I
H
A
Rhesus Macaque
Macaca mulatta
XP_001113941
304
35284
T181
P
S
F
K
R
K
R
T
E
E
Q
Q
F
C
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U7
304
34716
T181
P
P
R
K
L
K
R
T
T
D
E
E
G
W
D
Rat
Rattus norvegicus
Q6AYF5
304
34884
T181
P
P
R
K
L
V
R
T
E
A
Q
E
G
W
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520515
304
34841
E179
A
V
K
R
Q
K
T
E
I
P
E
D
Q
E
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DDV1
291
33524
R168
A
Y
E
P
S
S
K
R
P
K
F
S
P
E
N
Zebra Danio
Brachydanio rerio
Q5XJ56
251
28410
E129
M
S
V
E
E
L
W
E
Y
F
C
A
D
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651693
327
37834
E168
E
V
K
E
L
Q
E
E
V
D
E
P
E
T
V
Honey Bee
Apis mellifera
XP_624367
267
31856
K145
S
L
F
I
K
E
V
K
K
D
N
K
I
I
T
Nematode Worm
Caenorhab. elegans
NP_496093
557
63487
F431
R
Q
G
T
A
I
I
F
P
S
K
S
A
I
S
Sea Urchin
Strong. purpuratus
XP_787673
347
40065
R202
T
C
F
W
R
G
Q
R
K
S
D
S
Y
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
98
N.A.
N.A.
73.6
75.3
N.A.
64.8
N.A.
55.5
47
N.A.
34.8
39.1
21.3
29.1
Protein Similarity:
100
74.3
99
N.A.
N.A.
86.5
85.1
N.A.
77.6
N.A.
71
60.8
N.A.
54.1
57.2
32.3
46.6
P-Site Identity:
100
0
93.3
N.A.
N.A.
46.6
46.6
N.A.
6.6
N.A.
0
6.6
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
6.6
100
N.A.
N.A.
60
46.6
N.A.
33.3
N.A.
20
13.3
N.A.
26.6
40
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
9
0
0
0
0
9
0
17
9
0
17
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
9
0
0
17
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
25
9
9
9
0
25
% D
% Glu:
9
0
9
17
17
9
9
25
25
17
25
25
9
17
0
% E
% Phe:
0
0
34
0
0
0
0
9
0
9
9
0
17
0
0
% F
% Gly:
0
0
9
0
0
9
0
9
0
0
0
0
17
9
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
0
0
0
9
0
9
9
0
9
0
0
0
17
17
0
% I
% Lys:
9
0
17
34
9
34
9
9
25
9
9
9
0
0
0
% K
% Leu:
0
9
0
0
25
9
0
0
0
0
0
0
0
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% N
% Pro:
34
17
9
9
0
0
0
0
17
9
0
9
9
0
0
% P
% Gln:
0
9
0
0
9
9
9
0
0
0
25
9
9
0
0
% Q
% Arg:
9
0
17
9
25
0
34
17
0
0
0
0
0
0
9
% R
% Ser:
9
25
0
0
9
9
0
0
0
25
0
25
0
0
17
% S
% Thr:
9
0
0
9
0
9
9
34
9
0
9
0
0
9
9
% T
% Val:
0
17
9
0
0
9
9
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
9
0
0
9
0
0
0
0
0
0
17
0
% W
% Tyr:
0
9
0
0
0
0
0
0
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _