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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTWD1
All Species:
20.91
Human Site:
Y124
Identified Species:
41.82
UniProt:
Q8N5C7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5C7
NP_001138427.1
304
35248
Y124
E
F
V
N
I
Y
T
Y
P
C
I
P
E
Y
E
Chimpanzee
Pan troglodytes
XP_510391
226
25925
R55
Q
K
A
Q
Q
S
G
R
S
K
C
L
K
C
G
Rhesus Macaque
Macaca mulatta
XP_001113941
304
35284
Y124
E
F
V
N
I
Y
T
Y
P
C
I
P
E
Y
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U7
304
34716
Y124
D
S
V
N
I
Y
T
Y
P
C
I
P
E
Y
E
Rat
Rattus norvegicus
Q6AYF5
304
34884
Y124
D
S
V
N
I
Y
T
Y
P
C
I
P
E
Y
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520515
304
34841
Y120
E
D
V
H
I
Y
T
Y
P
C
I
P
E
Y
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DDV1
291
33524
Y118
E
D
V
T
V
Y
T
Y
P
C
V
P
Q
Y
H
Zebra Danio
Brachydanio rerio
Q5XJ56
251
28410
K80
H
P
N
E
T
D
G
K
S
T
A
V
Q
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651693
327
37834
E110
D
I
P
D
Y
R
E
E
A
G
V
V
L
I
F
Honey Bee
Apis mellifera
XP_624367
267
31856
A96
E
I
D
G
K
S
T
A
I
H
A
A
I
L
A
Nematode Worm
Caenorhab. elegans
NP_496093
557
63487
H274
I
Y
L
H
F
G
F
H
V
V
L
E
E
L
D
Sea Urchin
Strong. purpuratus
XP_787673
347
40065
F130
D
A
V
S
L
E
E
F
T
P
R
P
A
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.3
98
N.A.
N.A.
73.6
75.3
N.A.
64.8
N.A.
55.5
47
N.A.
34.8
39.1
21.3
29.1
Protein Similarity:
100
74.3
99
N.A.
N.A.
86.5
85.1
N.A.
77.6
N.A.
71
60.8
N.A.
54.1
57.2
32.3
46.6
P-Site Identity:
100
0
100
N.A.
N.A.
86.6
86.6
N.A.
86.6
N.A.
60
0
N.A.
0
13.3
6.6
20
P-Site Similarity:
100
13.3
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
N.A.
80
13.3
N.A.
20
13.3
46.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
9
9
0
17
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
9
0
0
9
0
% C
% Asp:
34
17
9
9
0
9
0
0
0
0
0
0
0
0
9
% D
% Glu:
42
0
0
9
0
9
17
9
0
0
0
9
50
0
50
% E
% Phe:
0
17
0
0
9
0
9
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
0
9
17
0
0
9
0
0
0
0
9
% G
% His:
9
0
0
17
0
0
0
9
0
9
0
0
0
0
9
% H
% Ile:
9
17
0
0
42
0
0
0
9
0
42
0
9
9
0
% I
% Lys:
0
9
0
0
9
0
0
9
0
9
0
0
9
9
9
% K
% Leu:
0
0
9
0
9
0
0
0
0
0
9
9
9
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
34
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
50
9
0
59
0
0
0
% P
% Gln:
9
0
0
9
9
0
0
0
0
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
9
0
9
0
0
9
0
0
0
0
% R
% Ser:
0
17
0
9
0
17
0
0
17
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
9
0
59
0
9
9
0
0
0
0
0
% T
% Val:
0
0
59
0
9
0
0
0
9
9
17
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
9
50
0
50
0
0
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _