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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTWD1 All Species: 18.48
Human Site: Y274 Identified Species: 36.97
UniProt: Q8N5C7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5C7 NP_001138427.1 304 35248 Y274 K E K Y R G Q Y D N L L F F Y
Chimpanzee Pan troglodytes XP_510391 226 25925 T197 N D S K C K G T T L K K I I F
Rhesus Macaque Macaca mulatta XP_001113941 304 35284 Y274 K E K Y R G Q Y D N L L F F Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9D8U7 304 34716 Y274 K E K Y R G Q Y D N L L F F Y
Rat Rattus norvegicus Q6AYF5 304 34884 Y274 K E E Y R G Q Y D N L L F F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520515 304 34841 Y272 K E Q Y T G Q Y D N L L F F Y
Chicken Gallus gallus
Frog Xenopus laevis Q6DDV1 291 33524 K261 Y H T K I L Q K D Y K G E Y D
Zebra Danio Brachydanio rerio Q5XJ56 251 28410 E222 L H C H Y F C E Y T G E Y D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651693 327 37834 G261 G L N T A Y R G L D N L E I T
Honey Bee Apis mellifera XP_624367 267 31856 D238 R Y K G Q Y D D L L Y F F K Y
Nematode Worm Caenorhab. elegans NP_496093 557 63487 F524 G R K Y S G E F D D L L Y W F
Sea Urchin Strong. purpuratus XP_787673 347 40065 R295 K V T R I S R R W P A G R I N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.3 98 N.A. N.A. 73.6 75.3 N.A. 64.8 N.A. 55.5 47 N.A. 34.8 39.1 21.3 29.1
Protein Similarity: 100 74.3 99 N.A. N.A. 86.5 85.1 N.A. 77.6 N.A. 71 60.8 N.A. 54.1 57.2 32.3 46.6
P-Site Identity: 100 0 100 N.A. N.A. 100 93.3 N.A. 86.6 N.A. 13.3 0 N.A. 6.6 20 40 6.6
P-Site Similarity: 100 13.3 100 N.A. N.A. 100 100 N.A. 93.3 N.A. 20 13.3 N.A. 20 33.3 80 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 9 0 9 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 9 9 59 17 0 0 0 9 9 % D
% Glu: 0 42 9 0 0 0 9 9 0 0 0 9 17 0 0 % E
% Phe: 0 0 0 0 0 9 0 9 0 0 0 9 50 42 17 % F
% Gly: 17 0 0 9 0 50 9 9 0 0 9 17 0 0 0 % G
% His: 0 17 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 17 0 0 0 0 0 0 0 9 25 0 % I
% Lys: 50 0 42 17 0 9 0 9 0 0 17 9 0 9 0 % K
% Leu: 9 9 0 0 0 9 0 0 17 17 50 59 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 0 0 42 9 0 0 0 17 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 9 0 9 0 50 0 0 0 0 0 0 0 0 % Q
% Arg: 9 9 0 9 34 0 17 9 0 0 0 0 9 0 0 % R
% Ser: 0 0 9 0 9 9 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 17 9 9 0 0 9 9 9 0 0 0 0 9 % T
% Val: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % W
% Tyr: 9 9 0 50 9 17 0 42 9 9 9 0 17 9 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _