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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAB3 All Species: 5.45
Human Site: S183 Identified Species: 12
UniProt: Q8N5C8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5C8 NP_690000.2 712 78683 S183 S P P P P P P S Y M H I P R Y
Chimpanzee Pan troglodytes XP_001173115 701 77714 L181 F N P I M V T L A P N I Q T G
Rhesus Macaque Macaca mulatta XP_001096046 685 75743 A171 Q T G M N P S A M Q G P S P P
Dog Lupus familis XP_548926 717 79117 I188 P P P S Y M H I P R Y S T N P
Cat Felis silvestris
Mouse Mus musculus Q571K4 716 79011 I187 P P P S Y M H I P R Y S T N P
Rat Rattus norvegicus Q5U303 693 76310 L181 F N P I M V T L A P N I Q T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506810 639 67882 G132 P R S A P A L G A A G A S G R
Chicken Gallus gallus XP_416787 711 78523 T178 A M Q G P P P T Y M H I P R Y
Frog Xenopus laevis Q7ZXH3 692 76689 M162 P G V G T S A M Q A S L P T Y
Zebra Danio Brachydanio rerio Q5RFW2 711 76862 T180 N T G R N T P T S L H I H G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796526 546 60608 I39 P T N L N L C I T Q L K E R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.8 95.3 97 N.A. 94.6 34.6 N.A. 65.3 83.9 68.4 33.5 N.A. N.A. N.A. N.A. 25
Protein Similarity: 100 49.7 95.7 98 N.A. 96 51.4 N.A. 71.7 89.4 79.3 49.5 N.A. N.A. N.A. N.A. 38.6
P-Site Identity: 100 13.3 6.6 13.3 N.A. 13.3 13.3 N.A. 6.6 66.6 13.3 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 20 13.3 20 N.A. 20 20 N.A. 6.6 80 20 40 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 10 10 10 28 19 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 19 19 0 0 0 10 0 0 19 0 0 19 28 % G
% His: 0 0 0 0 0 0 19 0 0 0 28 0 10 0 0 % H
% Ile: 0 0 0 19 0 0 0 28 0 0 0 46 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 10 0 10 10 19 0 10 10 10 0 0 0 % L
% Met: 0 10 0 10 19 19 0 10 10 19 0 0 0 0 0 % M
% Asn: 10 19 10 0 28 0 0 0 0 0 19 0 0 19 0 % N
% Pro: 46 28 46 10 28 28 28 0 19 19 0 10 28 10 28 % P
% Gln: 10 0 10 0 0 0 0 0 10 19 0 0 19 0 0 % Q
% Arg: 0 10 0 10 0 0 0 0 0 19 0 0 0 28 10 % R
% Ser: 10 0 10 19 0 10 10 10 10 0 10 19 19 0 10 % S
% Thr: 0 28 0 0 10 10 19 19 10 0 0 0 19 28 0 % T
% Val: 0 0 10 0 0 19 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 19 0 0 0 19 0 19 0 0 0 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _