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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAB3 All Species: 17.88
Human Site: S579 Identified Species: 39.33
UniProt: Q8N5C8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5C8 NP_690000.2 712 78683 S579 E E M T R L R S M N R Q L Q I
Chimpanzee Pan troglodytes XP_001173115 701 77714 M568 L K S E V N E M E N N L T R R
Rhesus Macaque Macaca mulatta XP_001096046 685 75743 S552 E E M T R L R S M N R Q L Q I
Dog Lupus familis XP_548926 717 79117 S584 E E M T R L R S M N R Q L Q I
Cat Felis silvestris
Mouse Mus musculus Q571K4 716 79011 S583 E E M T R L R S T N R Q L Q I
Rat Rattus norvegicus Q5U303 693 76310 K560 M Q K K K L D K L K S E V N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506810 639 67882 E510 N V D C T L K E V D L L Q S R
Chicken Gallus gallus XP_416787 711 78523 S580 E E M T K L R S L N R Q L Q I
Frog Xenopus laevis Q7ZXH3 692 76689 N560 M T R L R G L N R Q L Q I N V
Zebra Danio Brachydanio rerio Q5RFW2 711 76862 E578 K L K E E V N E M E S D L T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796526 546 60608 E417 T E E Q V K L E R M R G E I R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.8 95.3 97 N.A. 94.6 34.6 N.A. 65.3 83.9 68.4 33.5 N.A. N.A. N.A. N.A. 25
Protein Similarity: 100 49.7 95.7 98 N.A. 96 51.4 N.A. 71.7 89.4 79.3 49.5 N.A. N.A. N.A. N.A. 38.6
P-Site Identity: 100 6.6 100 100 N.A. 93.3 6.6 N.A. 6.6 86.6 13.3 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 20 100 100 N.A. 93.3 40 N.A. 26.6 100 33.3 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 0 0 10 0 10 0 0 0 % D
% Glu: 46 55 10 19 10 0 10 28 10 10 0 10 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 46 % I
% Lys: 10 10 19 10 19 10 10 10 0 10 0 0 0 0 0 % K
% Leu: 10 10 0 10 0 64 19 0 19 0 19 19 55 0 0 % L
% Met: 19 0 46 0 0 0 0 10 37 10 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 10 10 0 55 10 0 0 19 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 10 0 0 0 0 0 10 0 55 10 46 0 % Q
% Arg: 0 0 10 0 46 0 46 0 19 0 55 0 0 10 37 % R
% Ser: 0 0 10 0 0 0 0 46 0 0 19 0 0 10 0 % S
% Thr: 10 10 0 46 10 0 0 0 10 0 0 0 10 10 0 % T
% Val: 0 10 0 0 19 10 0 0 10 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _