KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDTC1
All Species:
18.79
Human Site:
S227
Identified Species:
31.79
UniProt:
Q8N5D0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5D0
NP_055838.2
677
75920
S227
H
R
K
S
M
K
Q
S
P
S
A
G
V
H
T
Chimpanzee
Pan troglodytes
XP_524629
677
75901
S227
H
R
K
S
M
K
Q
S
P
S
A
G
V
H
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544473
679
76002
S227
H
R
K
S
M
K
Q
S
P
S
A
G
V
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZK9
677
75714
S227
H
R
K
S
M
R
Q
S
P
S
A
G
V
H
T
Rat
Rattus norvegicus
Q5U2M6
591
66137
C168
A
R
F
V
Y
E
A
C
G
A
R
V
F
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417728
671
75308
C227
H
R
K
S
M
K
Q
C
P
S
A
G
V
H
T
Frog
Xenopus laevis
Q6NRH1
601
67089
C177
T
R
F
I
Y
E
A
C
G
A
R
G
F
V
Q
Zebra Danio
Brachydanio rerio
NP_001124078
674
75722
S233
H
R
K
S
L
S
Q
S
S
S
A
G
V
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611296
628
71725
L204
I
G
V
R
L
L
N
L
H
D
Q
L
E
N
T
Honey Bee
Apis mellifera
XP_396989
658
74624
Y223
N
D
A
Y
I
R
M
Y
D
R
R
M
I
K
L
Nematode Worm
Caenorhab. elegans
NP_001021829
558
63400
E134
V
K
R
I
C
T
V
E
H
D
P
T
L
F
W
Sea Urchin
Strong. purpuratus
XP_001203929
540
60446
V117
C
S
D
S
C
N
N
V
L
I
N
L
N
Y
Y
Poplar Tree
Populus trichocarpa
XP_002306549
756
83566
L227
S
T
S
R
P
H
L
L
L
V
G
G
S
D
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568242
757
83812
L230
I
S
A
T
R
P
H
L
L
L
V
G
G
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
N.A.
99.2
N.A.
97
22.6
N.A.
N.A.
93.6
20.6
80.8
N.A.
36.3
49.1
29.2
28.8
Protein Similarity:
100
100
N.A.
99.4
N.A.
98.8
40.1
N.A.
N.A.
95.7
38.8
88.6
N.A.
51.7
65.4
47.5
39.5
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
6.6
N.A.
N.A.
93.3
13.3
80
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
N.A.
93.3
26.6
86.6
N.A.
20
26.6
20
13.3
Percent
Protein Identity:
26.5
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
42
N.A.
N.A.
42
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
0
0
15
0
0
15
43
0
0
0
8
% A
% Cys:
8
0
0
0
15
0
0
22
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
8
15
0
0
0
8
8
% D
% Glu:
0
0
0
0
0
15
0
8
0
0
0
0
8
0
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
15
8
0
% F
% Gly:
0
8
0
0
0
0
0
0
15
0
8
65
8
0
0
% G
% His:
43
0
0
0
0
8
8
0
15
0
0
0
0
43
0
% H
% Ile:
15
0
0
15
8
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
8
43
0
0
29
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
15
8
8
22
22
8
0
15
8
0
8
% L
% Met:
0
0
0
0
36
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
8
15
0
0
0
8
0
8
8
0
% N
% Pro:
0
0
0
0
8
8
0
0
36
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
43
0
0
0
8
0
0
0
15
% Q
% Arg:
0
58
8
15
8
15
0
0
0
8
22
0
0
0
0
% R
% Ser:
8
15
8
50
0
8
0
36
8
43
0
0
8
8
0
% S
% Thr:
8
8
0
8
0
8
0
0
0
0
0
8
0
0
50
% T
% Val:
8
0
8
8
0
0
8
8
0
8
8
8
43
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
15
0
0
8
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _