KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM57
All Species:
23.64
Human Site:
S631
Identified Species:
74.29
UniProt:
Q8N5G2
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5G2
NP_060672.2
664
76178
S631
I
T
Y
S
A
A
T
S
P
L
S
P
V
S
P
Chimpanzee
Pan troglodytes
Q2TLZ5
664
76145
S631
I
T
Y
S
A
A
T
S
P
L
S
P
V
S
P
Rhesus Macaque
Macaca mulatta
Q2TLZ4
664
76182
S631
I
T
Y
S
A
A
T
S
P
L
S
P
V
S
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQE6
664
76070
S631
I
T
Y
S
A
A
T
S
P
L
S
P
V
S
P
Rat
Rattus norvegicus
Q4V7D3
664
76064
S631
I
T
Y
S
A
A
T
S
P
L
S
P
V
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001072063
676
76303
S643
I
S
Y
T
A
D
T
S
S
M
T
P
V
A
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395855
714
82057
T661
D
T
F
G
P
A
P
T
C
T
T
S
K
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797147
685
77481
N652
Q
P
Q
Q
Q
R
S
N
P
G
T
P
P
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
N.A.
N.A.
99.2
98.6
N.A.
N.A.
N.A.
N.A.
N.A.
81.5
N.A.
45.3
N.A.
35.4
Protein Similarity:
100
100
99.8
N.A.
N.A.
99.6
99.4
N.A.
N.A.
N.A.
N.A.
N.A.
89.5
N.A.
63.1
N.A.
53.2
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
75
75
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
13
0
0
0
0
0
13
0
0
0
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
63
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
0
13
0
13
0
75
0
0
88
13
13
75
% P
% Gln:
13
0
13
13
13
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
13
% R
% Ser:
0
13
0
63
0
0
13
75
13
0
63
13
0
63
0
% S
% Thr:
0
75
0
13
0
0
75
13
0
13
38
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _