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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRSX
All Species:
21.21
Human Site:
S169
Identified Species:
35.9
UniProt:
Q8N5I4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5I4
NP_660160.2
330
36443
S169
L
L
D
T
L
K
E
S
G
S
P
G
H
S
A
Chimpanzee
Pan troglodytes
XP_528624
709
76900
S221
L
V
D
T
L
K
E
S
G
S
P
G
H
S
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852222
387
42342
S221
L
L
D
T
L
K
E
S
G
A
P
G
R
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBZ0
335
35939
S169
L
L
P
A
L
R
A
S
G
A
E
G
R
G
S
Rat
Rattus norvegicus
NP_001101507
316
35239
F152
G
V
N
H
L
G
H
F
L
L
T
Y
L
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506622
336
37117
T155
L
L
E
N
L
K
K
T
G
S
P
S
Y
N
A
Chicken
Gallus gallus
Q5F389
414
46711
S251
E
D
I
L
R
R
S
S
P
A
R
V
V
V
V
Frog
Xenopus laevis
NP_001087360
327
35999
S167
L
L
K
T
M
K
K
S
G
T
E
N
L
N
A
Zebra Danio
Brachydanio rerio
Q803A8
412
46303
A248
Q
D
V
L
R
L
S
A
P
A
R
V
V
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLU5
409
46492
K249
L
E
T
L
F
D
Y
K
T
R
I
I
V
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798545
322
35072
K145
N
L
L
L
D
K
L
K
A
S
A
P
S
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42536
405
43844
A241
T
G
N
T
N
T
L
A
G
N
V
P
P
K
A
Baker's Yeast
Sacchar. cerevisiae
Q08651
330
37466
L158
F
I
F
T
M
R
L
L
P
L
L
R
H
C
R
Red Bread Mold
Neurospora crassa
Q92247
412
44615
T226
L
L
P
L
L
Q
K
T
A
E
E
T
G
E
T
Conservation
Percent
Protein Identity:
100
37.2
N.A.
67.4
N.A.
56.4
39
N.A.
65.4
29.7
63.9
30.1
N.A.
26.4
N.A.
N.A.
39.3
Protein Similarity:
100
41.7
N.A.
75.4
N.A.
71.6
53.9
N.A.
77.9
42.5
78.1
41
N.A.
40.5
N.A.
N.A.
56.6
P-Site Identity:
100
93.3
N.A.
80
N.A.
40
6.6
N.A.
53.3
6.6
46.6
0
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
86.6
N.A.
60
20
N.A.
86.6
20
73.3
13.3
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.6
25.7
23.7
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43
39.3
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
15
15
29
8
0
0
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% C
% Asp:
0
15
22
0
8
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
8
0
0
0
22
0
0
8
22
0
0
8
0
% E
% Phe:
8
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
8
0
0
50
0
0
29
8
8
0
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
0
22
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
8
8
0
0
8
% I
% Lys:
0
0
8
0
0
43
22
15
0
0
0
0
0
8
0
% K
% Leu:
58
50
8
36
50
8
22
8
8
15
8
0
15
15
8
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
15
8
8
0
0
0
0
8
0
8
0
15
0
% N
% Pro:
0
0
15
0
0
0
0
0
22
0
29
15
8
0
0
% P
% Gln:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
15
22
0
0
0
8
15
8
15
8
8
% R
% Ser:
0
0
0
0
0
0
15
43
0
29
0
8
8
15
15
% S
% Thr:
8
0
8
43
0
8
0
15
8
8
8
8
0
0
8
% T
% Val:
0
15
8
0
0
0
0
0
0
0
8
15
22
15
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _