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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHRSX All Species: 22.73
Human Site: Y202 Identified Species: 38.46
UniProt: Q8N5I4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5I4 NP_660160.2 330 36443 Y202 D L Q S S A C Y S P H A A Y A
Chimpanzee Pan troglodytes XP_528624 709 76900 Y581 D L Q S S A C Y S P H A A Y A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852222 387 42342 Y254 D L Q G S R C Y S P H A A Y A
Cat Felis silvestris
Mouse Mus musculus Q8VBZ0 335 35939 Y202 D L H G R H A Y S P Y A A Y A
Rat Rattus norvegicus NP_001101507 316 35239 F185 H L G G K I R F H D L Q S K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506622 336 37117 Y188 D L Q N S R C Y T P Q G A Y A
Chicken Gallus gallus Q5F389 414 46711 K284 F S L L S P S K K E Y W A M L
Frog Xenopus laevis NP_001087360 327 35999 Y200 D L N S S Y C Y S P H G A Y A
Zebra Danio Brachydanio rerio Q803A8 412 46303 Q281 L D L L S P P Q K N Y W S L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 Y282 L S P P P E K Y W S M M A Y N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798545 322 35072 S178 N S D Q R Y N S A E A Y A N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 F274 A M I D G G D F V G A K A Y K
Baker's Yeast Sacchar. cerevisiae Q08651 330 37466 Y191 K L S K T W D Y K P N M L F T
Red Bread Mold Neurospora crassa Q92247 412 44615 I259 Q F K S L E E I N E D V G P N
Conservation
Percent
Protein Identity: 100 37.2 N.A. 67.4 N.A. 56.4 39 N.A. 65.4 29.7 63.9 30.1 N.A. 26.4 N.A. N.A. 39.3
Protein Similarity: 100 41.7 N.A. 75.4 N.A. 71.6 53.9 N.A. 77.9 42.5 78.1 41 N.A. 40.5 N.A. N.A. 56.6
P-Site Identity: 100 100 N.A. 86.6 N.A. 60 6.6 N.A. 66.6 13.3 80 6.6 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 86.6 N.A. 66.6 20 N.A. 80 20 80 20 N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 24.6 25.7 23.7
Protein Similarity: N.A. N.A. N.A. 40.2 43 39.3
P-Site Identity: N.A. N.A. N.A. 13.3 20 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 40 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 15 8 0 8 0 15 29 72 0 43 % A
% Cys: 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 % C
% Asp: 43 8 8 8 0 0 15 0 0 8 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 15 8 0 0 22 0 0 0 0 0 % E
% Phe: 8 8 0 0 0 0 0 15 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 22 8 8 0 0 0 8 0 15 8 0 0 % G
% His: 8 0 8 0 0 8 0 0 8 0 29 0 0 0 0 % H
% Ile: 0 0 8 0 0 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 8 8 0 8 8 22 0 0 8 0 8 15 % K
% Leu: 15 58 15 15 8 0 0 0 0 0 8 0 8 8 15 % L
% Met: 0 8 0 0 0 0 0 0 0 0 8 15 0 8 0 % M
% Asn: 8 0 8 8 0 0 8 0 8 8 8 0 0 8 15 % N
% Pro: 0 0 8 8 8 15 8 0 0 50 0 0 0 8 0 % P
% Gln: 8 0 29 8 0 0 0 8 0 0 8 8 0 0 0 % Q
% Arg: 0 0 0 0 15 15 8 0 0 0 0 0 0 0 0 % R
% Ser: 0 22 8 29 50 0 8 8 36 8 0 0 15 0 8 % S
% Thr: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 8 0 0 15 0 0 0 % W
% Tyr: 0 0 0 0 0 15 0 58 0 0 22 8 0 58 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _