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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM63A
All Species:
22.12
Human Site:
Y222
Identified Species:
48.67
UniProt:
Q8N5J2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5J2
NP_001035307.1
469
51805
Y222
T
G
V
S
D
F
E
Y
T
P
E
C
S
V
F
Chimpanzee
Pan troglodytes
XP_524866
641
70108
Y394
T
G
V
S
D
F
E
Y
T
P
E
C
S
V
F
Rhesus Macaque
Macaca mulatta
XP_001106845
328
36130
L82
L
G
P
T
L
G
T
L
P
E
V
E
T
M
R
Dog
Lupus familis
XP_540306
462
50638
S215
N
V
R
F
T
G
V
S
D
F
E
Y
T
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q76LS9
468
51207
Y222
T
G
V
S
D
F
E
Y
T
P
E
C
S
I
F
Rat
Rattus norvegicus
Q5BJQ2
482
52710
Y236
T
G
V
S
D
F
E
Y
T
P
E
C
S
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506263
277
31353
I31
K
E
E
S
T
P
I
I
T
Q
N
E
N
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KQS4
520
57347
Y274
T
G
V
S
D
F
E
Y
T
P
E
C
I
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500023
379
42002
G133
E
T
F
E
A
N
L
G
D
V
M
N
I
M
E
Sea Urchin
Strong. purpuratus
XP_791130
551
60178
Y257
T
G
V
K
D
F
E
Y
T
Q
E
C
V
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08930
360
41014
M114
S
F
E
N
T
K
E
M
S
I
F
R
L
F
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
65.6
84.2
N.A.
85.7
81.9
N.A.
38.1
N.A.
N.A.
52.6
N.A.
N.A.
N.A.
29.2
39.9
Protein Similarity:
100
72.6
67.5
88.4
N.A.
89.9
86.3
N.A.
47.3
N.A.
N.A.
65
N.A.
N.A.
N.A.
45.6
53.3
P-Site Identity:
100
100
6.6
6.6
N.A.
93.3
100
N.A.
13.3
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
0
80
P-Site Similarity:
100
100
26.6
13.3
N.A.
100
100
N.A.
20
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
6.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% C
% Asp:
0
0
0
0
55
0
0
0
19
0
0
0
0
0
0
% D
% Glu:
10
10
19
10
0
0
64
0
0
10
64
19
0
0
19
% E
% Phe:
0
10
10
10
0
55
0
0
0
10
10
0
0
10
55
% F
% Gly:
0
64
0
0
0
19
0
10
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
10
0
0
19
10
0
% I
% Lys:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
10
0
10
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
19
0
% M
% Asn:
10
0
0
10
0
10
0
0
0
0
10
10
10
0
10
% N
% Pro:
0
0
10
0
0
10
0
0
10
46
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% R
% Ser:
10
0
0
55
0
0
0
10
10
0
0
0
37
0
0
% S
% Thr:
55
10
0
10
28
0
10
0
64
0
0
0
19
0
0
% T
% Val:
0
10
55
0
0
0
10
0
0
10
10
0
10
46
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _