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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPIC All Species: 17.27
Human Site: Y116 Identified Species: 76
UniProt: Q8N5J4 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5J4 NP_689536.1 248 29180 Y116 K K L R L F E Y L H E S L Y N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001084463 315 36209 Y183 K K L R L F E Y L H E S L C N
Dog Lupus familis XP_854994 249 29049 Y117 K K L R L F E Y L H E S L C N
Cat Felis silvestris
Mouse Mus musculus Q6P3D7 242 27924 F115 G R R K L R L F E Y L F E S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506702 260 30417 Y128 K K L R L F E Y L Y E S L S D
Chicken Gallus gallus XP_425488 279 32356 Y147 K K L R L F E Y L H E S L Y D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 77.1 87.9 N.A. 66.1 N.A. N.A. 68 59.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 78.4 92.7 N.A. 80.2 N.A. N.A. 80 71.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 6.6 N.A. N.A. 80 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 93.3 N.A. 33.3 N.A. N.A. 93.3 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % D
% Glu: 0 0 0 0 0 0 84 0 17 0 84 0 17 0 0 % E
% Phe: 0 0 0 0 0 84 0 17 0 0 0 17 0 0 0 % F
% Gly: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 84 84 0 17 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 84 0 100 0 17 0 84 0 17 0 84 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 17 17 84 0 17 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 84 0 34 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 0 34 0 0 0 34 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _