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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CISD2
All Species:
23.64
Human Site:
S36
Identified Species:
52
UniProt:
Q8N5K1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5K1
NP_001008389.1
135
15278
S36
G
F
A
R
L
T
V
S
E
W
L
R
L
L
P
Chimpanzee
Pan troglodytes
XP_001160242
111
12709
L32
G
T
A
A
I
G
Y
L
A
Y
K
R
F
Y
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852575
244
27488
S145
G
F
A
R
L
T
V
S
E
W
L
R
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQB5
135
15224
S36
G
F
A
R
L
T
V
S
D
W
L
R
L
L
P
Rat
Rattus norvegicus
B0K020
108
12078
L29
G
T
A
A
L
G
Y
L
A
Y
K
K
F
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506904
146
16446
A47
K
F
L
T
S
A
L
A
K
W
L
R
L
L
P
Chicken
Gallus gallus
XP_420668
134
15229
S36
G
F
L
R
L
T
V
S
E
W
L
R
L
L
P
Frog
Xenopus laevis
Q6PCF8
135
15348
S36
G
F
I
R
L
T
V
S
E
W
L
R
L
L
P
Zebra Danio
Brachydanio rerio
Q7T326
135
15466
S36
G
F
A
R
L
T
V
S
E
W
L
R
L
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAM6
133
14614
A38
L
S
F
K
D
W
L
A
L
I
P
P
T
V
V
Honey Bee
Apis mellifera
XP_394113
130
14413
T42
W
I
A
L
I
P
P
T
A
L
V
A
G
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.6
N.A.
54.9
N.A.
96.3
47.4
N.A.
72.5
94.8
91.1
80
N.A.
47.4
44.4
N.A.
N.A.
Protein Similarity:
100
59.2
N.A.
55.3
N.A.
99.2
60
N.A.
80.8
97
95.5
90.3
N.A.
67.4
68.1
N.A.
N.A.
P-Site Identity:
100
20
N.A.
100
N.A.
93.3
20
N.A.
46.6
93.3
93.3
100
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
33.3
N.A.
66.6
93.3
93.3
100
N.A.
26.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
64
19
0
10
0
19
28
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% E
% Phe:
0
64
10
0
0
0
0
0
0
0
0
0
19
0
0
% F
% Gly:
73
0
0
0
0
19
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
19
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
10
0
0
10
0
0
0
0
10
0
19
10
0
0
0
% K
% Leu:
10
0
19
10
64
0
19
19
10
10
64
0
64
64
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
0
10
10
0
0
64
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
55
0
0
0
0
0
0
0
73
0
0
0
% R
% Ser:
0
10
0
0
10
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
19
0
10
0
55
0
10
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
55
0
0
0
10
0
0
10
19
% V
% Trp:
10
0
0
0
0
10
0
0
0
64
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
0
0
19
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _