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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CISD2
All Species:
27.27
Human Site:
S69
Identified Species:
60
UniProt:
Q8N5K1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5K1
NP_001008389.1
135
15278
S69
K
K
K
Q
Q
K
D
S
L
I
N
L
K
I
Q
Chimpanzee
Pan troglodytes
XP_001160242
111
12709
A62
D
N
P
K
I
V
H
A
F
D
M
E
D
L
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852575
244
27488
S178
K
K
K
Q
Q
K
D
S
L
I
N
L
K
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQB5
135
15224
S69
K
K
K
Q
Q
K
D
S
L
I
N
L
K
I
Q
Rat
Rattus norvegicus
B0K020
108
12078
A59
D
N
P
K
V
V
H
A
F
D
M
E
D
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506904
146
16446
S80
K
K
K
Q
Q
K
D
S
L
I
N
L
K
I
Q
Chicken
Gallus gallus
XP_420668
134
15229
S69
K
K
K
Q
Q
K
D
S
L
I
N
L
K
I
Q
Frog
Xenopus laevis
Q6PCF8
135
15348
S69
K
K
K
Q
Q
K
D
S
L
I
N
L
K
I
Q
Zebra Danio
Brachydanio rerio
Q7T326
135
15466
S69
K
K
K
K
Q
R
D
S
L
I
N
L
K
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAM6
133
14614
N74
A
K
N
S
G
R
C
N
N
H
I
R
K
N
E
Honey Bee
Apis mellifera
XP_394113
130
14413
K73
L
V
N
L
S
V
K
K
D
V
N
K
V
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.6
N.A.
54.9
N.A.
96.3
47.4
N.A.
72.5
94.8
91.1
80
N.A.
47.4
44.4
N.A.
N.A.
Protein Similarity:
100
59.2
N.A.
55.3
N.A.
99.2
60
N.A.
80.8
97
95.5
90.3
N.A.
67.4
68.1
N.A.
N.A.
P-Site Identity:
100
0
N.A.
100
N.A.
100
0
N.A.
100
100
100
86.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
100
N.A.
100
20
N.A.
100
100
100
100
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
0
64
0
10
19
0
0
19
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
19
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
64
10
0
0
64
0
% I
% Lys:
64
73
64
28
0
55
10
10
0
0
0
10
73
0
0
% K
% Leu:
10
0
0
10
0
0
0
0
64
0
0
64
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% M
% Asn:
0
19
19
0
0
0
0
10
10
0
73
0
0
10
0
% N
% Pro:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
55
64
0
0
0
0
0
0
0
0
0
64
% Q
% Arg:
0
0
0
0
0
19
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
10
0
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
28
0
0
0
10
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _