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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf23
All Species:
35.45
Human Site:
S122
Identified Species:
70.91
UniProt:
Q8N5L8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5L8
NP_680544.1
163
17631
S122
P
A
V
W
V
L
L
S
R
D
P
L
D
P
N
Chimpanzee
Pan troglodytes
XP_510676
199
20600
S140
P
G
L
A
I
L
L
S
K
D
A
L
D
P
R
Rhesus Macaque
Macaca mulatta
XP_001104161
163
17616
S122
P
A
V
W
V
L
L
S
R
D
P
L
D
P
N
Dog
Lupus familis
XP_538708
163
17693
S122
P
A
V
W
V
L
L
S
R
D
P
L
D
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99JH1
163
17657
S122
P
A
V
W
V
L
L
S
R
D
P
L
D
P
S
Rat
Rattus norvegicus
Q5PPN2
199
20920
S140
P
S
L
A
I
L
L
S
K
D
A
L
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518454
201
21546
S122
P
A
I
C
V
L
L
S
K
D
P
L
D
A
R
Chicken
Gallus gallus
XP_424977
181
20019
S122
P
A
I
C
V
L
L
S
K
D
A
L
D
P
Q
Frog
Xenopus laevis
NP_001087536
186
20922
S122
P
T
I
C
V
L
L
S
K
D
P
L
D
P
T
Zebra Danio
Brachydanio rerio
NP_001002540
224
24351
S141
P
S
I
W
V
L
L
S
R
D
S
L
D
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724490
206
23128
D128
L
H
I
L
M
S
L
D
E
L
P
D
T
I
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798043
237
27106
R194
G
S
M
A
Q
R
K
R
Q
K
K
R
G
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.6
96.9
95.7
N.A.
94.4
39.7
N.A.
53.2
45.8
47.3
40.6
N.A.
30.5
N.A.
N.A.
32.4
Protein Similarity:
100
54.7
97.5
95.7
N.A.
96.3
56.2
N.A.
62.1
61.3
62.9
52.2
N.A.
46.5
N.A.
N.A.
43.8
P-Site Identity:
100
53.3
100
100
N.A.
93.3
53.3
N.A.
66.6
66.6
66.6
73.3
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
73.3
100
100
N.A.
100
80
N.A.
80
80
80
86.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
25
0
0
0
0
0
0
25
0
0
9
0
% A
% Cys:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
84
0
9
84
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
42
0
17
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
9
0
42
9
9
0
0
9
0
% K
% Leu:
9
0
17
9
0
84
92
0
0
9
0
84
0
0
0
% L
% Met:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% N
% Pro:
84
0
0
0
0
0
0
0
0
0
59
0
0
67
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
17
% Q
% Arg:
0
0
0
0
0
9
0
9
42
0
0
9
0
0
25
% R
% Ser:
0
25
0
0
0
9
0
84
0
0
9
0
0
0
9
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% T
% Val:
0
0
34
0
67
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _