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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf23
All Species:
13.64
Human Site:
S149
Identified Species:
27.27
UniProt:
Q8N5L8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5L8
NP_680544.1
163
17631
S149
L
G
S
M
P
S
S
S
C
G
P
R
S
R
R
Chimpanzee
Pan troglodytes
XP_510676
199
20600
P167
P
S
S
P
P
A
A
P
T
S
K
R
S
L
G
Rhesus Macaque
Macaca mulatta
XP_001104161
163
17616
S149
L
G
S
M
P
S
S
S
C
G
P
R
S
R
R
Dog
Lupus familis
XP_538708
163
17693
S149
L
G
P
T
S
S
S
S
C
G
P
R
P
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99JH1
163
17657
S149
L
G
S
I
P
S
P
S
C
G
P
R
P
R
R
Rat
Rattus norvegicus
Q5PPN2
199
20920
S167
P
S
S
P
P
T
V
S
T
S
K
R
S
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518454
201
21546
P149
P
D
T
P
D
P
S
P
P
A
D
T
P
A
P
Chicken
Gallus gallus
XP_424977
181
20019
A149
F
W
I
E
T
L
K
A
E
S
Q
A
Q
M
K
Frog
Xenopus laevis
NP_001087536
186
20922
E149
H
W
I
Q
E
L
R
E
Q
E
T
P
R
R
K
Zebra Danio
Brachydanio rerio
NP_001002540
224
24351
E168
L
W
I
Q
A
L
K
E
E
A
A
T
P
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724490
206
23128
Q155
D
G
G
G
A
Q
Q
Q
P
H
P
R
S
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798043
237
27106
D221
S
G
G
D
R
T
K
D
G
G
K
E
E
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.6
96.9
95.7
N.A.
94.4
39.7
N.A.
53.2
45.8
47.3
40.6
N.A.
30.5
N.A.
N.A.
32.4
Protein Similarity:
100
54.7
97.5
95.7
N.A.
96.3
56.2
N.A.
62.1
61.3
62.9
52.2
N.A.
46.5
N.A.
N.A.
43.8
P-Site Identity:
100
26.6
100
73.3
N.A.
80
33.3
N.A.
6.6
0
6.6
13.3
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
40
100
73.3
N.A.
86.6
40
N.A.
13.3
13.3
13.3
13.3
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
9
9
9
0
17
9
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% C
% Asp:
9
9
0
9
9
0
0
9
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
9
9
0
0
17
17
9
0
9
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
17
9
0
0
0
0
9
42
0
0
0
0
17
% G
% His:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
0
25
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
25
0
0
0
25
0
0
9
25
% K
% Leu:
42
0
0
0
0
25
0
0
0
0
0
0
0
17
0
% L
% Met:
0
0
0
17
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
25
0
9
25
42
9
9
17
17
0
42
9
34
0
17
% P
% Gln:
0
0
0
17
0
9
9
9
9
0
9
0
9
9
0
% Q
% Arg:
0
0
0
0
9
0
9
0
0
0
0
59
9
50
34
% R
% Ser:
9
17
42
0
9
34
34
42
0
25
0
0
42
0
0
% S
% Thr:
0
0
9
9
9
17
0
0
17
0
9
17
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _