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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf23 All Species: 9.09
Human Site: S154 Identified Species: 18.18
UniProt: Q8N5L8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5L8 NP_680544.1 163 17631 S154 S S S C G P R S R R R A R D T
Chimpanzee Pan troglodytes XP_510676 199 20600 S172 A A P T S K R S L G E P A A G
Rhesus Macaque Macaca mulatta XP_001104161 163 17616 S154 S S S C G P R S R R R A R D T
Dog Lupus familis XP_538708 163 17693 P154 S S S C G P R P R R R V R D T
Cat Felis silvestris
Mouse Mus musculus Q99JH1 163 17657 P154 S P S C G P R P R R R A R D T
Rat Rattus norvegicus Q5PPN2 199 20920 S172 T V S T S K R S L G E S A A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518454 201 21546 P154 P S P P A D T P A P L G P L G
Chicken Gallus gallus XP_424977 181 20019 Q154 L K A E S Q A Q M K R K Q G G
Frog Xenopus laevis NP_001087536 186 20922 R154 L R E Q E T P R R K R W P P G
Zebra Danio Brachydanio rerio NP_001002540 224 24351 P173 L K E E A A T P R H G Q R R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724490 206 23128 S160 Q Q Q P H P R S Q P R H Q Q Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798043 237 27106 E226 T K D G G K E E K K E N R E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.6 96.9 95.7 N.A. 94.4 39.7 N.A. 53.2 45.8 47.3 40.6 N.A. 30.5 N.A. N.A. 32.4
Protein Similarity: 100 54.7 97.5 95.7 N.A. 96.3 56.2 N.A. 62.1 61.3 62.9 52.2 N.A. 46.5 N.A. N.A. 43.8
P-Site Identity: 100 13.3 100 86.6 N.A. 86.6 20 N.A. 6.6 6.6 13.3 13.3 N.A. 26.6 N.A. N.A. 13.3
P-Site Similarity: 100 26.6 100 86.6 N.A. 86.6 33.3 N.A. 6.6 26.6 20 13.3 N.A. 40 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 0 17 9 9 0 9 0 0 25 17 17 0 % A
% Cys: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 9 0 0 0 0 0 0 0 34 0 % D
% Glu: 0 0 17 17 9 0 9 9 0 0 25 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 42 0 0 0 0 17 9 9 0 9 42 % G
% His: 0 0 0 0 9 0 0 0 0 9 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 25 0 0 0 25 0 0 9 25 0 9 0 0 9 % K
% Leu: 25 0 0 0 0 0 0 0 17 0 9 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % N
% Pro: 9 9 17 17 0 42 9 34 0 17 0 9 17 9 0 % P
% Gln: 9 9 9 9 0 9 0 9 9 0 0 9 17 9 9 % Q
% Arg: 0 9 0 0 0 0 59 9 50 34 59 0 50 9 0 % R
% Ser: 34 34 42 0 25 0 0 42 0 0 0 9 0 0 0 % S
% Thr: 17 0 0 17 0 9 17 0 0 0 0 0 0 0 34 % T
% Val: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _