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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf23 All Species: 29.7
Human Site: S60 Identified Species: 59.39
UniProt: Q8N5L8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5L8 NP_680544.1 163 17631 S60 R H V V F S G S G R A A G K A
Chimpanzee Pan troglodytes XP_510676 199 20600 C70 R A I V F S G C G R A T T K T
Rhesus Macaque Macaca mulatta XP_001104161 163 17616 S60 R H V V F S G S G R A A G K A
Dog Lupus familis XP_538708 163 17693 S60 R H V V F S G S G R A A G K A
Cat Felis silvestris
Mouse Mus musculus Q99JH1 163 17657 S60 R H V V F S G S G R A A G K A
Rat Rattus norvegicus Q5PPN2 199 20920 C70 R A I V F S G C G R A T T K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518454 201 21546 S60 R A V L F S G S G R A V G K T
Chicken Gallus gallus XP_424977 181 20019 S60 R Q I L F T G S G K A V S K T
Frog Xenopus laevis NP_001087536 186 20922 S60 R Q M L F V G S G R A L G K T
Zebra Danio Brachydanio rerio NP_001002540 224 24351 V79 R Q I V F T G V G Q S V A K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724490 206 23128 S67 R C V V W S G S G G G V V K T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798043 237 27106 T64 R S I I F T G T G T A I T K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.6 96.9 95.7 N.A. 94.4 39.7 N.A. 53.2 45.8 47.3 40.6 N.A. 30.5 N.A. N.A. 32.4
Protein Similarity: 100 54.7 97.5 95.7 N.A. 96.3 56.2 N.A. 62.1 61.3 62.9 52.2 N.A. 46.5 N.A. N.A. 43.8
P-Site Identity: 100 60 100 100 N.A. 100 60 N.A. 73.3 46.6 60 46.6 N.A. 53.3 N.A. N.A. 40
P-Site Similarity: 100 66.6 100 100 N.A. 100 66.6 N.A. 80 73.3 73.3 73.3 N.A. 60 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 0 0 0 0 0 0 0 84 34 9 0 42 % A
% Cys: 0 9 0 0 0 0 0 17 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 92 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 100 0 100 9 9 0 50 0 0 % G
% His: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 42 9 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 0 0 0 100 0 % K
% Leu: 0 0 0 25 0 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 25 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 100 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 67 0 67 0 0 9 0 9 0 0 % S
% Thr: 0 0 0 0 0 25 0 9 0 9 0 17 25 0 59 % T
% Val: 0 0 50 67 0 9 0 9 0 0 0 34 9 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _