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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf23 All Species: 33.64
Human Site: T109 Identified Species: 67.27
UniProt: Q8N5L8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5L8 NP_680544.1 163 17631 T109 D T G L D P L T V R R H V P A
Chimpanzee Pan troglodytes XP_510676 199 20600 S127 G E P A A S L S V L K N V P G
Rhesus Macaque Macaca mulatta XP_001104161 163 17616 T109 D T G L D P L T V R C H V P A
Dog Lupus familis XP_538708 163 17693 T109 D T G L D P L T V R R H V P A
Cat Felis silvestris
Mouse Mus musculus Q99JH1 163 17657 T109 D T G L D P L T V R R H V P A
Rat Rattus norvegicus Q5PPN2 199 20920 S127 S D P A A S L S V L K N V P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518454 201 21546 T109 D A G L D R L T V R R N L P A
Chicken Gallus gallus XP_424977 181 20019 T109 E A G L D A L T V K R N I P A
Frog Xenopus laevis NP_001087536 186 20922 T109 D V G L D P L T V R R N C P T
Zebra Danio Brachydanio rerio NP_001002540 224 24351 T128 G A G L D S L T V S R N V P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724490 206 23128 T115 G L E E I I V T R Q I P T L H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798043 237 27106 Q181 A R S V N Q R Q D R D G Q G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.6 96.9 95.7 N.A. 94.4 39.7 N.A. 53.2 45.8 47.3 40.6 N.A. 30.5 N.A. N.A. 32.4
Protein Similarity: 100 54.7 97.5 95.7 N.A. 96.3 56.2 N.A. 62.1 61.3 62.9 52.2 N.A. 46.5 N.A. N.A. 43.8
P-Site Identity: 100 26.6 93.3 100 N.A. 100 26.6 N.A. 73.3 60 73.3 60 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 46.6 93.3 100 N.A. 100 53.3 N.A. 86.6 86.6 80 73.3 N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 0 17 17 9 0 0 0 0 0 0 0 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % C
% Asp: 50 9 0 0 67 0 0 0 9 0 9 0 0 0 0 % D
% Glu: 9 9 9 9 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 25 0 67 0 0 0 0 0 0 0 0 9 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 9 % H
% Ile: 0 0 0 0 9 9 0 0 0 0 9 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 17 0 0 0 0 % K
% Leu: 0 9 0 67 0 0 84 0 0 17 0 0 9 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 50 0 0 0 % N
% Pro: 0 0 17 0 0 42 0 0 0 0 0 9 0 84 0 % P
% Gln: 0 0 0 0 0 9 0 9 0 9 0 0 9 0 0 % Q
% Arg: 0 9 0 0 0 9 9 0 9 59 59 0 0 0 0 % R
% Ser: 9 0 9 0 0 25 0 17 0 9 0 0 0 0 25 % S
% Thr: 0 34 0 0 0 0 0 75 0 0 0 0 9 0 9 % T
% Val: 0 9 0 9 0 0 9 0 84 0 0 0 59 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _