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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf23 All Species: 20.61
Human Site: T25 Identified Species: 41.21
UniProt: Q8N5L8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5L8 NP_680544.1 163 17631 T25 M P Q L P P D T L E M R V R D
Chimpanzee Pan troglodytes XP_510676 199 20600 A35 F A D L A P G A V H M R V K E
Rhesus Macaque Macaca mulatta XP_001104161 163 17616 T25 M P Q L P P D T L E M R V R D
Dog Lupus familis XP_538708 163 17693 T25 M P Q L P P D T L E M R V R D
Cat Felis silvestris
Mouse Mus musculus Q99JH1 163 17657 T25 M P Q L P P D T L E M R V R D
Rat Rattus norvegicus Q5PPN2 199 20920 A35 F A D L A P G A V H M R V K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518454 201 21546 T25 F P G L P P G T V Q M R V K D
Chicken Gallus gallus XP_424977 181 20019 I25 F T D L P P D I I E M K V K D
Frog Xenopus laevis NP_001087536 186 20922 I25 I T G L A Q D I I E M K V Q E
Zebra Danio Brachydanio rerio NP_001002540 224 24351 T25 F P D L P S D T P E V R V K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724490 206 23128 F32 M P K S Q K D F L W M H V K G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798043 237 27106 V29 L G V R F G E V I T M K V R N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38.6 96.9 95.7 N.A. 94.4 39.7 N.A. 53.2 45.8 47.3 40.6 N.A. 30.5 N.A. N.A. 32.4
Protein Similarity: 100 54.7 97.5 95.7 N.A. 96.3 56.2 N.A. 62.1 61.3 62.9 52.2 N.A. 46.5 N.A. N.A. 43.8
P-Site Identity: 100 33.3 100 100 N.A. 100 33.3 N.A. 60 53.3 33.3 60 N.A. 40 N.A. N.A. 20
P-Site Similarity: 100 53.3 100 100 N.A. 100 53.3 N.A. 80 73.3 66.6 73.3 N.A. 53.3 N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 25 0 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 34 0 0 0 67 0 0 0 0 0 0 0 59 % D
% Glu: 0 0 0 0 0 0 9 0 0 59 0 0 0 0 25 % E
% Phe: 42 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 9 17 0 0 9 25 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 17 0 9 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 17 25 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 9 0 0 0 0 0 25 0 50 0 % K
% Leu: 9 0 0 84 0 0 0 0 42 0 0 0 0 0 0 % L
% Met: 42 0 0 0 0 0 0 0 0 0 92 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 59 0 0 59 67 0 0 9 0 0 0 0 0 0 % P
% Gln: 0 0 34 0 9 9 0 0 0 9 0 0 0 9 0 % Q
% Arg: 0 0 0 9 0 0 0 0 0 0 0 67 0 42 0 % R
% Ser: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 17 0 0 0 0 0 50 0 9 0 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 9 25 0 9 0 100 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _