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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf23
All Species:
31.52
Human Site:
Y133
Identified Species:
63.03
UniProt:
Q8N5L8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5L8
NP_680544.1
163
17631
Y133
L
D
P
N
E
C
G
Y
Q
P
P
G
A
P
P
Chimpanzee
Pan troglodytes
XP_510676
199
20600
Y151
L
D
P
R
Q
P
G
Y
Q
P
P
N
P
H
P
Rhesus Macaque
Macaca mulatta
XP_001104161
163
17616
Y133
L
D
P
N
E
C
G
Y
Q
P
P
R
A
P
P
Dog
Lupus familis
XP_538708
163
17693
Y133
L
D
P
N
E
C
G
Y
Q
P
P
G
A
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99JH1
163
17657
Y133
L
D
P
S
E
C
G
Y
Q
P
P
G
A
P
P
Rat
Rattus norvegicus
Q5PPN2
199
20920
Y151
L
D
P
R
Q
L
G
Y
Q
P
P
N
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518454
201
21546
Y133
L
D
A
R
Q
D
G
Y
Q
P
P
D
P
R
P
Chicken
Gallus gallus
XP_424977
181
20019
Y133
L
D
P
Q
E
P
G
Y
Q
A
P
G
S
F
D
Frog
Xenopus laevis
NP_001087536
186
20922
Y133
L
D
P
T
Q
P
G
Y
Q
P
P
G
A
C
D
Zebra Danio
Brachydanio rerio
NP_001002540
224
24351
Y152
L
D
K
N
Q
P
G
Y
Q
A
P
G
S
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724490
206
23128
K139
D
T
I
D
G
L
Q
K
P
N
T
S
T
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798043
237
27106
G205
R
G
D
Q
K
D
K
G
R
T
P
G
E
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.6
96.9
95.7
N.A.
94.4
39.7
N.A.
53.2
45.8
47.3
40.6
N.A.
30.5
N.A.
N.A.
32.4
Protein Similarity:
100
54.7
97.5
95.7
N.A.
96.3
56.2
N.A.
62.1
61.3
62.9
52.2
N.A.
46.5
N.A.
N.A.
43.8
P-Site Identity:
100
60
93.3
100
N.A.
93.3
60
N.A.
53.3
60
66.6
53.3
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
66.6
93.3
100
N.A.
100
66.6
N.A.
60
66.6
73.3
66.6
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
17
0
0
42
0
0
% A
% Cys:
0
0
0
0
0
34
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
84
9
9
0
17
0
0
0
0
0
9
0
9
25
% D
% Glu:
0
0
0
0
42
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
9
% F
% Gly:
0
9
0
0
9
0
84
9
0
0
0
59
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
9
0
9
9
0
0
0
0
0
9
0
% K
% Leu:
84
0
0
0
0
17
0
0
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
34
0
0
0
0
0
9
0
17
0
0
0
% N
% Pro:
0
0
67
0
0
34
0
0
9
67
92
0
17
34
59
% P
% Gln:
0
0
0
17
42
0
9
0
84
0
0
0
0
0
9
% Q
% Arg:
9
0
0
25
0
0
0
0
9
0
0
9
0
9
0
% R
% Ser:
0
0
0
9
0
0
0
0
0
0
0
9
17
9
0
% S
% Thr:
0
9
0
9
0
0
0
0
0
9
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _