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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAMKK1
All Species:
24.24
Human Site:
T446
Identified Species:
53.33
UniProt:
Q8N5S9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5S9
NP_115670.1
505
55735
T446
R
L
I
P
S
W
T
T
V
I
L
V
K
S
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091843
505
55717
T446
R
L
I
P
S
W
T
T
V
I
L
V
K
S
M
Dog
Lupus familis
XP_868554
482
53098
V426
S
E
E
E
H
C
S
V
V
E
V
T
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBY2
505
55819
T446
R
L
I
P
S
W
T
T
V
I
L
V
K
S
M
Rat
Rattus norvegicus
P97756
505
55889
T446
K
L
I
P
S
W
T
T
V
I
L
V
K
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519677
851
91898
T642
K
L
I
P
S
L
T
T
V
V
R
R
A
G
E
Chicken
Gallus gallus
XP_001234325
537
59761
A478
K
T
I
P
S
L
P
A
V
I
L
V
K
A
M
Frog
Xenopus laevis
NP_001082316
523
58635
T465
K
L
I
P
S
L
T
T
V
I
L
V
K
A
M
Zebra Danio
Brachydanio rerio
NP_001014361
434
48727
V378
S
L
S
A
V
I
L
V
K
A
M
L
R
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021153
541
60786
T448
R
V
I
P
R
L
D
T
L
I
L
V
K
A
M
Sea Urchin
Strong. purpuratus
XP_785473
661
73509
Q603
C
V
L
V
E
V
S
Q
D
E
V
D
S
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
89.5
N.A.
93.4
93.6
N.A.
38.4
69.4
69.4
63.5
N.A.
N.A.
N.A.
42.8
35.7
Protein Similarity:
100
N.A.
99.5
91.2
N.A.
95.8
95.8
N.A.
46.5
79.3
80.1
76
N.A.
N.A.
N.A.
59.7
50.3
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
93.3
N.A.
46.6
60
80
6.6
N.A.
N.A.
N.A.
60
0
P-Site Similarity:
100
N.A.
100
26.6
N.A.
100
100
N.A.
60
73.3
93.3
26.6
N.A.
N.A.
N.A.
80
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
10
0
0
10
28
0
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% D
% Glu:
0
10
10
10
10
0
0
0
0
19
0
0
10
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
73
0
0
10
0
0
0
64
0
0
0
0
10
% I
% Lys:
37
0
0
0
0
0
0
0
10
0
0
0
64
10
0
% K
% Leu:
0
64
10
0
0
37
10
0
10
0
64
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
64
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
73
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
37
0
0
0
10
0
0
0
0
0
10
10
10
0
10
% R
% Ser:
19
0
10
0
64
0
19
0
0
0
0
0
10
37
0
% S
% Thr:
0
10
0
0
0
0
55
64
0
0
0
10
0
0
0
% T
% Val:
0
19
0
10
10
10
0
19
73
10
19
64
0
0
0
% V
% Trp:
0
0
0
0
0
37
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _