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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D19
All Species:
36.97
Human Site:
S177
Identified Species:
67.78
UniProt:
Q8N5T2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5T2
NP_060787.2
526
60268
S177
Y
E
N
G
D
S
L
S
F
R
T
H
L
G
L
Chimpanzee
Pan troglodytes
XP_001166746
526
60188
S177
Y
E
N
G
D
S
L
S
F
R
T
H
L
G
L
Rhesus Macaque
Macaca mulatta
XP_001084301
526
60205
S177
Y
E
N
G
D
S
L
S
F
R
T
H
L
G
L
Dog
Lupus familis
XP_536268
525
59882
S176
Y
E
N
G
D
S
L
S
F
R
T
H
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_653100
526
60385
S177
Y
E
N
G
D
S
L
S
F
R
T
H
L
G
L
Rat
Rattus norvegicus
NP_001099478
526
60309
S177
Y
E
N
G
D
S
L
S
F
R
T
H
L
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514213
547
62259
S198
Y
E
N
G
D
Q
P
S
F
R
T
H
L
G
L
Chicken
Gallus gallus
XP_420750
526
60176
S177
Y
E
N
G
E
Q
L
S
F
R
N
H
L
G
L
Frog
Xenopus laevis
NP_001089246
527
60151
T178
Y
D
C
G
D
Q
G
T
Y
K
S
Y
L
G
L
Zebra Danio
Brachydanio rerio
NP_956785
526
60133
T177
T
E
R
S
D
D
L
T
V
K
S
H
W
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608913
509
58458
Q185
K
T
T
E
N
T
D
Q
I
P
Q
W
E
F
S
Honey Bee
Apis mellifera
XP_623591
536
62028
L187
F
K
K
Q
P
D
E
L
N
W
E
F
S
H
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191986
401
45886
V91
P
K
Q
R
Q
T
G
V
D
D
T
S
D
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
93.3
N.A.
97.3
97.7
N.A.
85.1
91.2
84.6
77.5
N.A.
39.9
43.2
N.A.
47.3
Protein Similarity:
100
100
100
95
N.A.
98.8
99.2
N.A.
89
95.8
93.1
87.2
N.A.
62.3
63
N.A.
61
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
40
40
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
86.6
80
60
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
70
16
8
0
8
8
0
0
8
0
0
% D
% Glu:
0
70
0
8
8
0
8
0
0
0
8
0
8
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
62
0
0
8
0
16
0
% F
% Gly:
0
0
0
70
0
0
16
0
0
0
0
0
0
77
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
70
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
8
16
8
0
0
0
0
0
0
16
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
62
8
0
0
0
0
70
0
77
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
62
0
8
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
8
0
8
0
0
8
0
0
0
0
8
% P
% Gln:
0
0
8
8
8
24
0
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
62
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
47
0
62
0
0
16
8
8
0
8
% S
% Thr:
8
8
8
0
0
16
0
16
0
0
62
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% W
% Tyr:
70
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _